https://www.thebody.com/health/hiv-dovato-dolutegravir-lamivudine
HIV MedicationsDovato

Dovato for HIV Treatment: Everything You Need to Know

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    Frequently Asked QuestionsDovato

    What is Dovato used for?

    Dovato is a complete single-tablet regimen (STR) and full antiretroviral (ARV) treatment used to control HIV. It was approved for use by the Food and Drug Administration (FDA) in 2019.

    How often is Dovato taken?

    Dovato is normally taken by mouth once a day, with no food or timing restrictions.

    What are the drugs in Dovato?

    Dovato contains two medications—lamivudine (3TC, Epivir) and dolutegravir (DTG, Tivicay).

    • 3TC is in the class of drugs called “nucleoside reverse transcriptase inhibitors” (NRTI), which block HIV from making copies of itself early in its life cycle.
    • DTG is in the class of drugs called “integrase strand transfer inhibitors” (INSTI), which stop HIV from making copies of itself later in the life cycle.

    What makes Dovato unique as an HIV treatment?

    Since 1997, the standard of care in HIV treatment has been three or four medications. Dovato is a big deal because it is the first full ARV regimen approved by the FDA for the treatment of HIV in ARV-naive patients that only contains two medications.

    David Malebranche, M.D., M.P.H.

    David Malebranche, M.D., M.P.H.

    David Malebranche, M.D., M.P.H., is a black same-gender-loving educator, author, activist, and internal medicine physician. He co-hosts the YouTube series 'Revolutionary Health' as part of The Counter Narrative Project and also appears on the #AskTheHIVDoc video series.