HIV MedicationsGenvoya

Genvoya for HIV Treatment: Everything You Need to Know

illustration of larger-than-life Genvoya bottle alongside a person holding a massive Genvoya pill
Lily Fulop

    Frequently Asked QuestionsGenvoya

    What is Genvoya used for?

    Genvoya is a complete single-tablet regimen (STR) for the treatment of HIV. It was approved for use by the Food and Drug Administration (FDA) in 2015.

    How often is Genvoya taken?

    Genvoya is normally taken by mouth once a day and is recommended to be taken with food, as this can help improve absorption. The important part is striving to take it around the same time every day.

    What are the drugs in Genvoya?

    Genvoya is a tablet containing four medications: cobicistat, emtricitabine, elvitegravir, and tenofovir alafenamide.

    • Elvitegravir, or EVG, is in the class of drugs called “integrase strand transfer inhibitors” (INSTI), which stop HIV from making copies of itself later in its life cycle.
    • Emtricitabine (FTC, Emtriva) and tenofovir alafenamide (TAF) are both in the class of drugs called “nucleoside reverse transcriptase inhibitors” (NRTI), which block HIV from making copies of itself early in its life cycle.
    • Cobicistat (COBI, Tybost) is not an HIV medication but a pharmacokinetic enhancer or “booster” that works to help the other HIV medications in Genvoya work better.

    Does Genvoya have any side effects I should worry about?

    Genvoya is generally well-tolerated, with the possibility of common side effects such as nausea, diarrhea, headache, and fatigue—all of which happen in less than 5% of people taking it.

    David Malebranche, M.D., M.P.H.

    David Malebranche, M.D., M.P.H.

    David Malebranche, M.D., M.P.H., is a black same-gender-loving educator, author, activist, and internal medicine physician. He co-hosts the YouTube series 'Revolutionary Health' as part of The Counter Narrative Project and also appears on the #AskTheHIVDoc video series.