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Nevirapine Precautions Published

Physicians starting patients on nevirapine (Viramune®) need to be aware of new precautions published in February 2004 by Boehringer Ingelheim. A nevirapine combination is recommended as an "alternative" antiretroviral starting regimen in the current ...

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IATEC Presents the 2NN Study Results

The non-nucleoside reverse transcriptase inhibitors (NNRTIs), Sustiva (efavirenz) and Viramune (nevaripine), are now very commonly used as part of first-line HAART regimens. Previously, there was no data directly comparing the two NNRTIs nor the comb...

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Nevirapine and Vivid Dreams

There are currently three licensed non-nucleoside reverse transcriptase inhibitors (NNRTIs or non-nukes) available:

delavirdine (Rescriptor) efavirenz (Sustiva) nevirapine (Viramune)

Of these three drugs, efavirenz is well known for its side ef...

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Boehringer Ingelheim Pharmaceuticals Withdraws AIDS Drug Application

Ridgefield, Conn.-based Boehringer Ingelheim Pharmaceuticals announced Friday that it was withdrawing its request that the US Food and Drug Administration approve the drug nevirapine for preventing mother-to-child HIV transmission. John Wecker of Boe...

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Let Nevirapine Do What It Does Best

S.J. Little, et al. Persistence of Transmitted Drug Resistance among Subjects With Primary HIV Infection Not Receiving Antiretroviral Therapy. 9th Retrovirus Conference, Seattle, 2002. Abstract 95.

A single-dose of the AIDS drug nevirapine when take...

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Severe Nevirapine Rash Found More Likely in Women Than Men

Although the non-nucleoside analogue nevirapine (Viramune) is an effective part of anti-HIV regimens, it is associated with a number of side effects, including the following:

rash fever ulcers in the mouth liver damage

The most common side ef...

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Sex Differences in Nevirapine Rash and Hepatitis

Last year, the AIDS world was rocked when news came that the South African Medicines Control Commission had halted a study of an experimental HIV drug after two women in the trial died and several others developed severe liver disease. Coming in the ...

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More Caution With Nevirapine

Nevirapine (Viramune) can be a useful part of anti-HIV treatment combinations. Unfortunately, nevirapine may cause a severe hypersensitivity reaction in less than 1% of people exposed to this drug. In some cases, severe skin rash and liver damage hav...

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Nevirapine (Viramune) Strengthens Warning on Liver, Skin Toxicities

On November 9 Boehringer Ingelheim Roxane Laboratories notified medical professionals that the FDA-required labeling for its drug nevirapine had strengthened its warnings about risks of liver and other toxicities, due to reported cases of serious or ...

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Nevirapine, Prednisone, and Rash

Findings from a recent study show that people taking prednisone with nevirapine (Viramune) were more likely to develop nevirapine-related rash compared to people not taking prednisone. Prednisone is commonly used to treat rash, a potentially harmful ...