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Resistance Testing

Resistance -- How It Happens Genotypic and Phenotypic Tests When Should I Get a Resistance Test? Limitations The Future

Studies show that only half of the people who use HIV drug cocktails get full benefit from them. One reason is that HIV...

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Salvage Conference Highlights

The 3rd International Workshop on Salvage Therapy for HIV Infection was held in Chicago in April. It's when you hit that third group of drugs that you're considered to be on "salvage" therapy. (The second combination of meds is being called the "seco...

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Novel Aspects of Resistance to Antiretroviral Agents

Selection of Zidovudine (ZDV, AZT) Resistance Mutations by ZDV- or Stavudine (d4T)-based Regimens and Relationship to Subsequent Virologic Response in ACTG 370 Slide Session 2111 Authored by V. A. Johnson, R. L. Bassett, J. L. Koel, R. A. R...

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What Is Antibiotic Resistance? Why Is It a Problem?

Since the 1940s, antibiotics have been the cornerstone of infectious disease therapy. Their remarkable healing power invites widespread and often inappropriate use, which leads to antibiotic resistance and consequent treatment complications.

Antibio...

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AZT and d4T Cross-Resistance

STEP has reported data in past articles suggesting that a history of either Retrovir® (AZT) or Zerit® (d4T) might create cross-resistance to the other drug. This is due to the specific mutations that can cause resistance to both of these drugs. A stu...

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Two Studies Shed Light on Development of d4T Resistance

Reverse transcriptase (RT) mutation patterns from ZDV-naive subjects failing d4T-containing regimens (Poster, TuPeA3014) Authored by J.E. Hernandez, A. Scarsella, J. Kaiser, L. Ross, R. Fisher, M. Johnson, N. Graham, M. St Clair Development o...

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ABT-378/Ritonavir and Efavirenz for Salvage Therapy in Patients Multiply-Exposed to PIs

ABT-378/ritonavir and efavirenz for salvage therapy in patients multiply-exposed to PIs (TuPeB3196) Authored by N. Clumek, P.M. Girard, A. Telenti, J. Rockstroh, S. Becker, A. Lazzarin, S. Brun, E. Sun, X.U. Yi

Some of the most exciting data p...

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A No-Nonsense Guide to HIV Drug Resistance Testing

A 22-page booklet on HIV drug-resistance testing, written by well-known AIDS activists Tim Horn and Spencer Cox and edited by resistance expert Douglas Richman, M.D., is available without charge.

HIV resistance tests are used to tell which drugs the...

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4th International Workshop on HIV Drug Resistance and Treatment Strategies

<#insert elements/confs/leftnavconfs.html#>The Body Covers:The 4th International Workshop on HIV Drug Resistance and Treatment StrategiesSitges, SpainJune 12-16, 2000Conference SummariesReports and Related ArticlesCal Cohen, M.D.Resistance is o...

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Prevalence of Drug Resistance High

The issue of drug resistance has been an important concern in the area of HIV/AIDS treatment for several years. Over time, HIV is able to alter its structure in a way that allows it to resist the effects of antiretroviral drugs. When resistance devel...