HIV Drugs In Development

The Latest

An Overview of Valproic Acid

Other Names: Depakene, Depakote, Depakote ER, Epival, VPA, divalproex sodium, valproate Drug Class: Latency-Reversing Agents Molecular Formula: C8 H16 O2 Registry Number: 99-66-1 (CAS) Chemical Name: 2-propylpentanoic acid Chemical Class: O...

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An Overview of PRO-140

Other Names: PA14 Drug Class: Entry Inhibitor Registry Number: 674782-26-4 (CAS) Organization: CytoDyn, Inc. Phase of Development: IIb/III

(Compound details obtained from ChemIDplus Advanced1, NIAID Therapeutics Database2, and CytoDyn website3, and ...

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An Overview of Tenofovir Alafenamide

Other Names: GS-7340, TAF, TFV alafenamide, prodrug of tenofovir, tenofovir alafenamide fumarate

Drug Class: Nucleoside Reverse Transcriptase Inhibitors

Molecular Formula: C21 H29 N6 O5 P

Registry Number: 379270-37-8 (CAS)

Chemical Name: isopropy...

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An Overview of Trogarzo (Ibalizumab-Uiyk)

Brand Name: Trogarzo Other Name(s): Hu5A8, IBA, Ibalizumab-uiyk, TMB-355, TNX-355 Drug Class: Post-attachment Inhibitor Company: TaiMed Biologics USA Corp.

WARNING:Ibalizumab can cause serious, life-threatening side effects, including changes in you...

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An Overview of Elvucitabine

Other Names: ACH-126443, ELV, L-F-D4C, beta-L-Fd4C, l(-)Fd4C Drug Class: Nucleoside Reverse Transcriptase Inhibitors Molecular Formula: C9 H10 F N3 O3 Registry Number: 181785-84-2 (CAS) Chemical Name: 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,...

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Juluca approval

Hi dr young, a new single pill drug called juluca has just been approved. It consists of doluegravir and rilpivirine. Any idea how this is more superior than doluegravir and truvada in terms of toxicity? Thank you.

By Benjamin Young, M.D., Ph.D.

An Overview of Cenicriviroc

Other Names: CVC, TAK-652, TBR-652, cenicriviroc mesylate Drug Class: Entry Inhibitor Molecular Formula: C41 H52 N4 O4 S Registry Number: 497223-25-3 (CAS) Chemical Name: (5E)-8-[4-(2-butoxyethoxy)phenyl]-1-isobutyl-N-[4-[(S)-(3-propylimidazol-4-...

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injectable antiretroviral therapy

I am excited about the injectable antiretroviral therapy, could you kindly provide an update on the development of this therapy. How far is the process. I have been HIV + for four years and 100% adherent but it starting to take its toll on me.

By Benjamin Young, M.D., Ph.D.

chosing the best available regimen

I ALWAYS like to be on the best latest regimen.,,, ( lucky to have insurance that pays ok) Doing well on triumeq... ( <20 cd4 780 37%, stable for many years) Started d4t/zerit/viracept in 1995? made changes as times changed, .. atripla. stribild, tiv...

By Benjamin Young, M.D., Ph.D.

HIV/AIDS Clinical Trials

Key PointsHIV/AIDS clinical trials are research studies that look at new ways to prevent, detect, or treat HIV/AIDS. Clinical trials are the fastest way to determine if new medical approaches to HIV/AIDS are safe and effective in people.Examples of...

By AIDSinfo