Approved HIV Medications
The Latest

HAART, Dyslipidemia, and Hyperglycemia
HAART has been associated with the frequent appearance of dyslipidemia -- elevated total and LDL cholesterol, decreased HDL cholesterol, elevated triglycerides -- as well as hyperglycemia leading to diabetes. Dr. Morris Shambelan from San Francisco s...

Quantifying Abnormalities Associated with Fat Redistribution Syndrome
Many reports attempted to quantify the types of abnormalities associated with fat redistribution syndrome. Dr. Norma Muurahainen of Serono Laboratories reported on a preliminary analysis of a detailed self-assessment questionnaire performed by 208 pa...

Growth Hormone (rhGH) and Fat Redistribution Syndrome
Several papers concerning growth hormone (rhGH) and fat redistribution syndrome were reported. Dr. Christine Wanke from Boston reported on improvement in fat redistribution syndrome in 10 patients treated with rhGH in an ongoing 12 week study. All su...

Treating Fat Redistribution Syndrome
Various treatments of fat redistribution syndrome-associated lipid disorders have been reported. A study from Paris showed moderate improvement in hypertriglyceridemia with dietary intervention comparable to that recommended for non-HIV associated hy...

Amprenavir (Agenerase)
What Is Amprenavir?
Amprenavir is a drug used as part of antiretroviral therapy (ART). It is also called Agenerase®. It was manufactured by GlaxoSmithKline.
Manufacture of amprenavir was discontinued in October 2007. It is being replaced by fosampr...

Non-Nucleoside Reverse Transcriptase Inhibitors in Development
Non-Nucleoside Reverse Transcriptase Inhibitors NNRTIs in Development NNRTIs No Longer in Development
Note: Several fact sheets describe drugs that are being tested against HIV:
Fact Sheet 410: nucleoside analog reverse transcriptase inhibito...

Protease Inhibitors in Development
Protease Inhibitors Protease Inhibitors in Development PIs No Longer in Development
NOTE: Several fact sheets describe drugs that are being tested against HIV:
Fact Sheet 410: nucleoside analog reverse transcriptase inhibitors (nukes) Fact ...

Agenerase (Amprenavir, APV)
Brand Name: AgeneraseCommon Name: amprenavirClass: HIV protease inhibitor (PI)Standard Dose: 1200 mg twice daily. The 150 mg soft gelatin capsules were taken off the market because of the new formulation (Lexiva), but the 50 mg capsule an...

New Drugs From Old Classes
A number of new drugs from existing classes are being studied. Here's a brief rundown of drugs that have started trials in people:
Nucleoside Analog Reverse Transcriptase Inhibitors (NRTIs)
Amdoxovir (DAPD): Early results from an ongoing Phase II s...

Agenerase (Amprenavir)
The 150-mg soft, gelatin capsule of Agenerase (shown) was large, cream-white, oblong, and imprinted with "GX CC2" on one side. However, beginning in 2005, the drug is only available in 50-mg capsules and as a flavored solution (mainly for pediatric u...