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Susan Little, M.D.

Dr. Little is an Assistant Adjunct Professor of Medicine in the Division of Infectious Diseases at University of California San Diego (UCSD) with a research interest in HIV infection. She is also an attending physician at the Veterans Affairs Medical Center in San Diego. Dr. Little graduated from Washington University School of Medicine and then did a residency in Internal Medicine at Barnes Hospital in St. Louis, Missouri. She did her Infectious Diseases Fellowship at UCSD, and is board-certified in Internal Medicine and Infectious Diseases. Dr. Little works at the UCSD Antiviral Research Center in San Diego and conducts clinical translational research trials which focus on increasing our understanding of the pathogenesis of acute or primary HIV infection. She works with a large international collaborative team to assess viral replication dynamics, transmitted drug resistance, and host immune dynamics during acute HIV infection. These studies also evaluate therapeutic intervention strategies including antiretroviral therapy and vaccines to preserve immune function in recently infected subjects. Her extensive research on drug resistance has been published in numerous journals and she has presented her findings at many international AIDS conferences Dr. Little has received most of her research funding from the NIH and the California Universitywide AIDS research Program (UARP). Pharmaceutical support for research has also been received from Merck Research Laboratories, Bristol-Myers Squibb, DuPont Pharmaceutical, Glaxo-Wellcome, and Agouron Pharmaceuticals.

Latest by Susan Little, M.D.

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hiv and having sex with others

what are the risk when you have sex nd your hiv+ can you get oder hiv infections and what are the and if you have hiv and hipititis b what are the risk

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CDC said normal cases 3 months, the rare cases 6 months and only 2 people 12 months. That is my knowledge of AIDS window period. One doctor said (Mar.2001) that he saw 2 years window period cases in Africa in an AIDS magazine. And he said, who knows ...

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Virtual phenotypes; what do they mean?

I learned not long ago that I was infected with hiv and a virtual phenotype revealed I was resistant to NNRTI since there was a long red bar next to Efavirenz, Nevirapine and Rescriptor. There was also milder resistance to the nukes and practically n...

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starting medication

Hi there,One quick question,If a person is diagnosed with hiv today,How long would they be able to stay drug free on average?(considering that the hiv they are infected with is not resistent to any drugs)looking forward to your reply

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Marked Weight Loss during ARS

Thank you in advance for helping me sort out my dilemma. I had receptive oral sex with a man of unknown HIV status mid-May 2002, no ejaculation but possible pre-ejaculate. Since about four weeks after that possible exposure, Ive had a constellation o...

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CD4/CD8 ratio and CD4

Dear Judith, I have been recently diagnosed HIV+ (June 02) and have some questions regarding both the CD4/CD8 ratio and CD4 which do not seem to be spoken about as much as the CD4 absolute. My first question is what exactly are CD8 cells? What happen...

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High Potassium Levels

Hi Doc, Two days ago i had my monthly bloods taken to measure VL and CD4 count. Today i received a call from my health care worker asking me to return on monday to have more blood taken as one of the tests revealed elevated potassium levels (5.9). I'...

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Wild Type Virus

I recently went off all meds due to mild pancreatitis. I am restarting meds in the next couple of weeks. I have very low t-cells..(20) and was wondering if there is any benefits/risks to being off drugs for 12 weeks so that my virus can return to wil...

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Seroconversion CD4 and Viral Loads

Dear Dr: I was exposed to HIV about 5 months ago and tested positive 3 months ago with severe symptoms; although I'm feeling much better now. My CD4 has been up and down between 163 and 264, and my viral load is still over 500,000. Until recently my...

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relationship between viral load and antibodies in diagnostics

Dr Little--- I understand that PCR is not a tool recommended for diagnosis of HIV. However, in the absence of antibodies (due to possible simultaneous co-infection) six months from exposure, would a quant PCR detect HIV down to 50 copies? Trying to u...