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San Francisco General Hospital

Latest by San Francisco General Hospital

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How to Use Condoms Correctly

Condoms are like cars: If you have an accident with one, the cause is almost certainly operator error, not mechanical failure. Indeed, the estimated failure rate of latex condoms is between 2% and 5% -- and when a condom does tear during intercourse,...

By San Francisco General Hospital
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Where the Rubber Meets the Road: Tips for Using Condoms

When used correctly, latex and polyurethane condoms stop the spread of HIV almost 100% of the time. Condoms are like cars: If you have an accident with one, the cause is almost certainly operator error, not mechanical failure. The estimated failure r...

By San Francisco General Hospital
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Optimal Medical Management: Entering the Era of Truly Individualized Antiretroviral Therapy

Over the past few years, there has been much speculation and debate about the potential role of drug-level monitoring in the optimal medical management of individuals with HIV infection. In its simplest form, so-called therapeutic drug monitoring, or...

By Andrew D. Luber, Pharm.D. and W. David Hardy, M.D. for San Francisco General Hospital
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Optimal Medical Management: Clinical Considerations in Therapeutic Drug Monitoring

Prior to ordering either a drug-level test or a phenotype for any patient, clinicians should evaluate the following

Patient Adherence

Both TDM and phenotyping are predicated on the assumption that the patient is taking all of his doses of all of hi...

By Andrew D. Luber, Pharm.D. and W. David Hardy, M.D. for San Francisco General Hospital
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Managing the Adverse Effects of Antiretroviral Therapy

Hypersensitivity Reactions Gastrointestinal Effects of Antiretroviral Therapy Pancreatitis Hematologic Effects of Therapy Renal Effects Peripheral Nervous System Effects Central Nervous System Effects Metabolic And Endocrine Effects ...

By M. Christine Jamjian, Pharm.D. and Spotswood L. Spruance, M.D. for San Francisco General Hospital
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Suffer the Children

When Incarnation Children's Center, a pediatric AIDS facility that serves one of New York City's most blighted neighborhoods, Washington Heights, opened in 1989, photographer Claire Yaffa was there. "She simply appeared on my doorstep," says Dr. Step...

By Claire Yaffa for San Francisco General Hospital
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OI Update: Toxoplasmosis

Toxoplasmosis is one of the most common opportunistic infections seen in patients with advanced HIV disease, especially in areas of the world where the rate of toxoplasma infection is high. It is also one of the most easily prevented OIs. Even before...

By Pablo Tebas, M.D. for San Francisco General Hospital
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Personal Stories

The Toughest Decision I Ever Made

My name is Rebecca, and I am HIV-positive. When I tested positive in 1990, the first thought that came into my head was "Does this mean that I can't have a baby?" I quickly turned my thoughts to other concerns: How long was I likely to live? Had I in...

By Rebecca Denison for San Francisco General Hospital
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A New Approach to Therapy

The good news is that we are now witnessing the first decrease in HIV/AIDS mortality since the inception of the epidemic seventeen years ago.(1, 2) The chief cause of this turnaround is the ability of powerful new multidrug antiretroviral regimens to...

By Stephen J. O'Brien, Ph.D. for San Francisco General Hospital
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Personal Stories

One Mother's Story

The first call came on a Wednesday night, about 10:30 New York time, in May of 1990. It came from Gretchen, my daughter-in-law of almost a year. She told me that her husband, my 24-year-old son Joseph, was in a hospital in Long Beach, California. Whe...

By Sherry B. Kopel for San Francisco General Hospital