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Bruce Dezube, M.D.

Dr. Bruce Dezube is an associate in medicine at Beth Israel Deaconess Medical Center (BIDMC) in Boston and an associate professor of medicine at Harvard Medical School. He is a prominent investigator and a major enroller in the multi-institutional AIDS Malignancy Consortium/NCI/NIH, a group whose mission is to create new approaches to therapy of AIDS-associated malignancies. He is also a founder of the NCI/NIH-funded AIDS Oncology subunit of the AIDS Malignancy Research and Treatment Center at BIDMC. After receiving an M.A. in chemistry from Harvard University, Dr. Dezube earned his M.D. at Tufts University Medical School. His postdoctoral training included an internship and residency at Tufts-New England Medical Center and a series of fellowships at Harvard Medical School, Beth Israel Hospital and the Dana-Farber Cancer Institute in Boston. He is board-certified in internal medicine, hematology, and oncology. Dr. Dezube is the national chair of several NIH protocols investigating the use of angiogenesis inhibitors in Kaposi's Sarcoma (KS). These trials resulted in several of the numerous reports, articles, and book chapters that he has authored and co-authored on AIDS-related malignancies. In addition, Dr. Dezube has delivered over 200 lectures and seminars and has given plenary talks on novel therapeutics for HIV disease, on international and national levels. He has lent his time to several community service endeavors, including work with the American Cancer Society AIDS Action Committee and the New England AIDS Education and Training Center. He is a frequent reviewer for the New England Journal of Medicine and the Journal of Clinical Oncology, among others. He has been awarded the American Cancer Society's Career Development Award and the National Cancer Institute's Clinical Trials Consortium Award for AIDS-Associated Malignancies. Dr. Dezube receives funding for his research from Agouron Pharmaceuticals, Cytran Inc., and Ligand Pharmaceuticals.

Latest by Bruce Dezube, M.D.

Q&A: Ask the Experts

Intermediate grade NHL

Dear Dr. Dezube, I have a history of Intermediate grade NHL. After chemotherapy, there was complete remission. Once again, after eight years, I have a few enlarged lymph nodes in my neck. I am in a peculiar situation wherein the opinions of two indep...

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Dr. Bruce Dezube's Farewell Message

This is my final post (see below). Bruce Dezube

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HIV progression/effect on lymph nodes

Dr. Dezube, Do you find that, as HIV disease progresses, lymph nodes no longer get enlarged, even if they are sensitive? If so, why is this? A breakdown in the ability of the body to defend itself? Thanks.

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Hemorrhoids or HPV

Hi, i am 18 years old and notice that my anus is slightly tighter, in the shower i felt a little bump inside the anus. I have never had anal sex, and i am a virgin. I was reading, and it could be either HPV or Hemorrhoids. I do not feel discomfort, p...

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Dying Husband with Lymphoma and Dementia; This may sound horrible, but I want him to die.

My husband is dying he was diagnosed at a very late stage Cd4 70s, viral load in the millions. My problem is unbeknown to me he had another wife in another state. She is negative and I am positive. This man literally did nothing to help himself in re...

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Not Alone Anymore In Montana

Forgive me if this is not the proper place to post but I wanted to get in touch with "Alone in Montana" ASAP. You are not alone! There are many other people in the state who are +. It's just we are all spread throughout the state. I have a non profit...

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Treatment for KS. Should I take chemotherapy or just rely on the fact that my immune system will improve?

I was diagnosed 7 weeks ago that I am HIV positive and that the small purple spots on my neck was KS. At that time my CD4 cell count was 143 and Viral load 438,080. After 5 weeks on medication my CD4 cell count went to 350 and my Viral load to 1300...

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Extremely large lymph node in groin; what's the next step?

I have been HIV positive since 1992. Three months ago I switched my antiretroviral therapy. The results in terms of CD4 cells and viral load have been very positive. About a week ago I noticed that one of the lymph nodes in my groin was extremely sw...

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Does KS need to be treated if it's only one spot?

doctor, do I need treatment if I have only one KS on my chest? I suspect it is KS because this 3mm spot has been there for several months and never go away. Thx.

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Bladder cancer treatment in an HIV positive patient. How do HIV drugs and chemotherapy go together?

My husband has been diagnosed with Stage 3-4 Bladder cancer. So far there is no evidence that the cancer has spread beyond the bladder wall, but he is advised to undergo bladder removal surgery. There are concerns that chemotherapy will complicated H...