Vaccine Recommendations for Adults Living With HIV Disease in the United States

Based on recommendations from the Centers for Disease Control (CDC).

VaccineRecommended for People With HIV?Number of VaccinationsAdditional Information
InfluenzaYesOne vaccination per yearFluMist®, a live attenuated influenza vaccine (LAIV) inhaled through the nose, should not be used by people with HIV
PneumococcalYesOne vaccination with a booster vaccination after five yearsVaccination is recommended soon after you find out you have HIV disease. The vaccine protects from pneumococcal infections in the lungs only.
Hepatitis B Virus (HBV)YesThree vaccinationsA blood test (HBV antibody test) can tell if you have been exposed to HBV. After completing the series, a blood test (antibody titer) will tell you if you need another booster shot for protection. (Note: Twinrix® is a three-shot hepatitis A/B combination vaccination.)
Hepatitis A (HAV)YesTwo vaccinationsA blood test (HAV antibody test) can tell if you have been exposed to HAV. Most doctors recommend an HAV vaccination for people living with HIV. (Note: Twinrix® is a three-shot hepatitis A/B combination vaccination.)
Tetanus/Diphtheria (Td)YesThree childhood vaccinations followed by one booster vaccination every 10 years 
Measles, Mumps and Rubella (MMR)DependsMMR is two vaccinations.
Rubella alone is one booster vaccination
Check your childhood and young adult medical history.
  • If you have already been fully vaccinated for MMR, you may not need another vaccination.
  • If you do not know or have not been completely vaccinated, talk with your doctor about whether or not the MMR vaccination series would be right for you.
People with no symptoms of HIV and CD4+ cells above 200, especially women planning on getting pregnant, should talk with their doctors about the rubella vaccination.

The CDC does NOT recommend the MMR vaccination (or other measles containing vaccines) for people living with HIV whose CD4+ cell count is either below 200 cells/mm3 or whose CD4+ cell percentage is below 14% of their total lymphocytes.
Varicella (the virus that causes chicken pox and shingles)NoOne to two doses depending on ageThe Varicella vaccine is currently NOT recommended for people living with HIV. If you have NOT had Varicella, avoid contact with children and adults who currently have either active chickenpox or shingles.