truvada to descovy

Question

my doctor switched me from truvada to descovy and my viral load became detectable after years of being undetectable, not to mention my cholesterol went up a lot and I'm experiencing terrible back pain of what seems to be my liver

Answer

The viral rebound and symptoms would be unusual to be due simply to the switch from Truvada to Descovy but nonetheless possible. Repeating the HIV level and checking for drug resistance would be recommended promptly. Back pain is often a nonspecific complaint and can be due to many conditions. Checking kidney function and a careful neurologic examination would be the first steps in evaluating the back pain symptom. Your HIV doctor should be made aware of your complaints since she/he can advise knowing your individual treatment and clinical history. KH