Hey Dr. Bob!
I must say, your work on this forum is wonderful; I admire every aspect of your responses and especially appreciate the humor I have found despite the severity of my situation! You tell it how it is!
I am currently a student in the bay area (from your post archives I believe you live close? - I live on the penninsula) Anyway exactly two weeks ago, I had a condom failure during receptive anal intercourse with a partner of unknown status. I freaked and went on PEP at 38 hours (Combivir and Kaletra). However, I am fearing the treatment is ineffective as I am starting to notice ARS symptoms: my lymph nodes in my neck, armpits, and groins, are gradually becomming noticable - although I have been rubbing and checking the areas constantly out of anxiety (this all began at 11 days post exposure). Today at day 14, I noticed a sore in the roof of my mouth. I have also had diarrhea for two days. My questions to you are: 1) are these symptoms and timing concurrent with ARS? 2) Is it unlikely to be experiencing ARS WHILE on PEP (wouldn't that presumably delay the progression of the virus until treatment is completed)? 3) Could the PEP itself be causing the gradually swelling nodes? 4) Are there any testing procedures I can have, other than antibody, to detect HIV now or sooner than 6 weeks? I am pretty scared and sleepless right now and would imemnsely appreciate a response. I know you will be totally honest and I really am just looking for some clarity right now. Thanks so much!!!
~ Scared Neighbor
ARS symptoms can begin several weeks after an exposure; however, your symptoms are much more consistent with anxiety than HIV ARS.
PEP does not "delay the progression of the virus (or symptoms) until treatment is completed." The purpose of PEP is to prevent HIV infection, not delay it.
No, Pep does not cause lymph node swelling, but it might contribute to your diarrhea.
If you had a significant HIV exposure (which, in your case, is not at all certain), started PEP and were experiencing symptoms consistent with ARS (which you are not), you could consider PCR testing. However, in your particular situation, my suggestion is for you follow the established PEP protocol for testing and follow up.
Getting some counseling and treatment for your anxiety and symptoms (insomnia, diarrhea, etc.) would be helpful during the period of uncertainty. You might also consider consulting an HIV specialist if you have not already done so for additional reassurance as well as additional information regarding PEP and your actual degree of risk.
You have done the responsible thing: using condoms for sex and getting immediate help shortly after a condom failed. Continually searching for HIV symptoms, however, is not helpful or reasonable and will only increase your anxiety. You need to stay levelheaded and realize that you are doing everything you can do for the moment. Stay focused on health, not illness. OK? The San Francisco Bay Area is one of the most spectacular places in the world to be. Shouldn't you be out enjoying this marvelous day? Take a stroll through Golden Gate Park, pet a dog, hug a tree, or have a cappuccino while watching the seals play on seal rock.
I'm here if you need me, neighbor.