Dr. Frascino,

You should be more cautious. Their statements do not redound to their credibility, but quite the opposite. Nobody is saying that ozone cures AIDS, at least as I understand, what you're saying is that ozone therapy is a useful complementary procedure in many diseases, including in AIDS. You will receive over the news that his life will be swallowing their manifestations as arrogant and unscientific. You ought to reconsider its quarter century devoted to the study of AIDS. Should you think. In medicine there is something true: "Just know that we know nothing." But you're right on one thing: medicine must prove everything scientifically, but it is equally true that only what can be economic benefit worth it. Honestly do you think anyone cares to spend hundreds of millions of dollars to show that ozone is effective for something. As something that can not be patented may be worth for Bayer, Merckx, Lilly, Sanofi, Glaxo, etc. You want you on a journey to prescribe this or that medication and I think very well, but obviously will not find any laboratory that prescribe visit to ozone. And finally add that ozone therapy is an alternative therapy. It is a complementary therapy. Yours sincerely

Dr. Juan Carlos


Hello Juan,

". . . At least as I understand, what you're saying is that ozone therapy is a useful complementary procedure in many diseases, including in AIDS." WHAT??? No Juan, that is definitely NOT what I'm saying. In fact I'm saying exactly the opposite. Ozone therapy is NOT at all useful in treating AIDS or any other disease! See below!

As for HIV specialist physicians not prescribing a visit for ozone treatments, I absolutely agree with them. The field of medicine is a scientific discipline based on reproducible fact, not pseudoscience myth.

Dr. Bob

does ozone help hepatitis c (OZONE) (OZONE THERAPY 2008) Dec 28, 2008

does ozone help in any way in the case of hepatitis c. also , can it hurt yu mentally or physically

Response from Dr. Frascino


Nope. In fact it doesn't help in any way for any disease process! See below.

Dr. Bob

Ozone Therapy Jun 23, 2007

Got a few questions;

How can it be said that Ozone Therapy is a Fraud?

Have you done any reseach on Ozone Therapy yourself?

Have you maybe through of trying to test the validity of Ozone Therapy yourself to prove if it does work or not?

I know for a fact that Ozone Therapy can NOT cure AIDS, but if a patient has been diagnosed with HIV and has a relatively high T cell count Ozone has been clinically proved to provide the patient with a stronger immune system to fight off secondary infections. These tests have been conduced in South Africa.

Ozone Therapy can be equated to when someone said the earth was round and was exciled because of it - well it seems he was right.

You can't say something doesn't work until you have tested it yourself. There are many horrible people out there who will use Ozone Therapy to their advantage to make money and not tell the whole truth or don't know all the facts. But the truth is Ozone Therapy has many many benefits and this can not be discredited.

Response from Dr. Frascino


  1. How can it be said that ozone therapy is a fraud? Easy. I just open my mouth and say (or flex my fingers and type), "OZONE IS A FRAUD." See, it's as easy as that. It's also the truth.

  2. Have I done any research on ozone therapy myself? Nope. Nor do I intend to, as it's been done many times before and has not shown any benefit in the treatment of HIV/AIDS.

  3. Should I test the validity of ozone therapy myself to prove it doesn't work? No, of course not. I'm also not going to waste my time testing unicorn blood, goat urine or Tasmanian devil vomit as potential HIV cures either.

  4. You know for a fact that ozone therapy has been clinically proven to provide stronger immune systems to fight off secondary infections??? Really??? Dearie, you can believe whatever you want, but that doesn't make it a scientific fact. I have seen no convincing scientific data from South Africa or anywhere else that supports your "fact."

  5. "You can't say something doesn't work until you have tested it yourself." What? Why not? Of course I can. Just see number 1 above! The scientific burden of proof does not rest on my personally disproving something when there is overwhelming scientific evidence already available doing just that.

As for "but the truth is ozone therapy has many, many benefits and this cannot be discredited." Well, actually it has indeed been discredited repeatedly with sound science and common sense. If you want to "believe" in ozone therapy, fine, that's your choice. But beliefs are not facts. Ozone therapy for any and all immune diseases is a fraud. Not only is it not helpful; it's potentially dangerous. (See below.)

Dr. Bob

Ozone is a highly unstable form of oxygen with disinfecting properties. Test tube studies suggest that it can damage viral particles and inhibit HIV's reverse transcriptase enzyme. Two research teams reported that in laboratory studies it inactivates HIV at concentrations which are non-toxic to human cells, but another team found that levels of ozone needed to kill animal viruses also resulted in 30% destruction of blood cells and haemoglobin.

Current use

Ozone is an unlicensed, experimental treatment. Despite the promising test-tube results, there is no clear evidence that ozone is a beneficial treatment for people with HIV. Two phase I studies showed no clear-cut effects on CD4 count or virus levels, and a phase II study showed no difference between the effects of ozone or placebo on a range of immunological and clinical measures.

Ozone has been promoted by individuals in several countries who charge large fees for treatment, despite the lack of evidence of efficacy. Claims have been made that people have been cured' through ozone treatment, but nocured' person has ever been produced for verification. There have also been reports of several deaths as a direct result of intravenous ozone infusions. Most AIDS specialists and groups for people with HIV advise extreme caution in the use of this treatment.

Taking it

Ozone can be administered in several different ways. Blood can be removed from the individual, exposed to ozone and then reinfused. Alternatively, a machine can be used which generates ozone gas and delivers it into the rectum, where it is thought to be absorbed through the mucous membranes. The most dangerous method consists of injecting ozone gas directly into the bloodstream. Hydrogen peroxide injections are also sometimes used as part of, or independently of, ozone therapy. Advocates of hydrogen peroxide also recommend drinking or bathing in it. However, doctors have reported one case in which a man with AIDS died after injecting himself with 35% hydrogen peroxide.

Key research

Wells reported that the antiviral effects of ozone include viral particle disruption, reverse transcriptase inactivation and/or a perturbation of the ability of the virus to bind to its receptor on target cells. Freeberg and Carpendale (1991) reported that ozone inactivated HIV at non-toxic concentrations, but Wagner found that at concentrations required to inhibit animal viruses, ozone induced 30 percent haemolysis and destruction of extracellular haemoglobin.

Bocci theorised that ozone induces the production of cytokines such as tumour necrosis factor (TNF) and interferon.

Carpendale (1993) reported that 4/5 HIV-positive men with diarrhoea of unknown origin improved when treated with ozone. However, the responders all had relatively high CD4 counts, and diarrhoea can resolve spontaneously, particularly at higher CD4 counts.

Garber performed a phase I study of ozone blood treatments in 10 HIV-positive individuals. No significant toxicity was observed. Three participants with moderate immunodeficiency showed improvement in surrogate markers. In a phase II controlled and randomized double-blinded study comparing reinjection of ozone-treated blood and reinjection of unprocessed blood for 8 weeks, followed by a 4-week observation period, ozone had no significant effect on haematologic, biochemical or clinical toxicity when compared with placebo. CD4 cell count, interleukin-2, interferon gamma, beta2-microglobulin, neopterin and p24 antigen were also unaffected by both treatment arms.

Hooker conducted an open study of ozone-treated blood in the treatment of 9 HIV-positive individuals. No significant change in mean absolute (or percentage) CD4 count was seen after 4 or 8 weeks of treatment. The HIV p24 antigen titre did not change significantly during treatment. One participant became weakly p24-antigenaemic during treatment, while another who was weakly antigenaemic at baseline became equivocal during therapy. The treatment was well tolerated; there was no bruising or local pain after the intramuscular injections.

Hirschtick reported the case of an individual who died after injecting himself with hydrogen peroxide.

Mayer reported the development of paranoid hallucinatory psychoses in a person receiving ozone therapy.


Bocci V. Ozonization of blood for the therapy of viral diseases and immunodeficiencies. Medical Hypotheses 39:30-34, 1992.

Carpendale MT et al. Ozone inactivates HIV at noncytotoxic concentrations. Antiviral Research 16(3):281-292, 1991.

Carpendale MT et al. Does ozone alleviate AIDS diarrhea? J Clin Gastroenterol 17(2):142-145, 1993.

Freeberg JK et al. Ozone inactivates extracellular human immunodeficiency virus at non-toxic concentrations. Fourth Intl Conf AIDS, Stockholm, abstract 3560, 1988.

Garber GE et al. The use of ozone-treated blood in the therapy of HIV infection and immune disease: a pilot study of safety and efficacy. AIDS 5:981-984, 1991.

Hirschtick RE et al. Death from an unconventional therapy for AIDS (letter). Ann Int Med 120(8):694, 1994.

Hooker MH et al. Ozone-treated blood in the treatment of HIV infection. AIDS 6:127-138, 1992.

Mayer C et al. Paranoid hallucinatory psychoses in an HIV infected patient on ozone therapy. Nervenarzt 62(3):194-197, 1991.

Wagner SJ et al. Virucidal levels of ozone induce hemolysis and hemoglobin degradation. Transfusion 31(8):748-751, 1991.

Wells KH et al. Inactivation of human immunodeficiency virus type 1 by ozone in vitro. Blood 78(7):1882-1890, 1991.

Ozone Therapy Feb 9, 2007

Hi doctor. What do you make of this? Is it done anywhere on the East coast?


Thank you!

Response from Dr. Frascino


Don't believe everything you read in the Tanzania Standard newspaper!

See below.

Dr. Bob

ozone Nov 13, 2006

HIV virus is anaerobic.... a method called major (autometharpy)<----- im not sure of the spelling.... a way where 250ml of your blood is taken infuse it or threat it with ozone.... and introduce it back to the patient.... obviously the virus are destroyed lowering your viral load, and an enhancing your cd4 count....to normal.... ozone resistance is imposible unlike medicines.... what can you say about this method doc...? some FDA officials uses these method... i think but in secret

Response from Dr. Frascino


Ozone therapy to treat HIV a secret? No, it's not a secret. It's a total fraud! If it really worked, don't you think I would have used it myself by now? Buyer beware! Ozone therapy is a total swindle!

Dr. Bob

Re: Ozone therapy Jun 26, 2007

Concerning your comments about triple therapy alternatives to Ozone. Its an availability issue.

1.Goats urine is not a problem, easy to come by and mixed with a little orange juice aint that bad.

2.Tasmanian devil vomit is a bit of a problem. The best is Extra Virgin Tasmanian Devil vomit (Rachael Ray refers to it as EVTDV) which can no longer be reliably obtained from Tasmania. Fortunately, I now have a supplier in Australia who sends it freeze-dried. Makes a decent quiche or tiramisu.

3.The greatest challenge is the Unicorns blood. Ive searched everywhere and believe it or not have been told by the naysayers that Unicorns DO NOT EXIST. Come onwhere do all those horns that we Italians wear around our necks come from? Ive been told to substitute pasteurized dragons milk, but hey I know that dragons are oviparous and not mammiferous. Im not stupid. Besides, Ive checked, its not in my grocers dairy case.

Alas, seems that Unicorns are as rare as hens teeth, especially molars.which are now, I understand, in early clinical trials, hopefully to be approved by the FDA and Perdue toward the end of this year.

(Sorry Bob, couldnt resist..from one Poz Italian MD to another.

Please keep me laughing.)

Ray (hey, we could do a radio show)

Response from Dr. Frascino

Hi Ray,

The real question I've been trying to answer for years is: Does each unicorn have a unique horn??? (Try saying it out loud.)

Keep smiling, Ray. It's the second (or perhaps third) best thing you can do with your lips.

Be well.

Dr. Bob

P. S.(Why settle for radio? With the Sopranos evaporating to a black screen, I'm sure HBO might be willing to offer us the Sunday night time slot.)