Question

Hi Dr McGowan,

Is there any study on the effects of melatonin supplements on viral load? Can melatonin supplements mask plasma viral load to undetectable? There was a paper a while ago that talked about a negative correlation between viral load and melatonin (Nunnari et all). I am paranoid because of a recent possible exposure, and am wondering if using melatonin supplements (~8 mg/day) could be a factor in an undetectable PCR RNA VL in the window period (~5 weeks), or if that's very, very unlikely. Thanks.

Answer

Hello Melatonin is not a factor in achieving an undetectable HIV-1 viral load. Thanks Joe