Factors that influence seroconversion?

Question

Could certain factors influence seroconversion to take longer than the normal six months window period such as extreme stress/anxiety, cancer/chemotherapy, or becoming infected with another STD or Hepatitis at the same point as becoming infected with HIV? Would these situations be a reason to test beyond the six month period. And, are there any other reasons that I have not listed that could delay seroconversion? Please respond! Thanks.

Answer

I doubt stress or STD coinfections would be a factor. Anything that makes B cells ( cells that make antibodies), or T cells and macrophages (cells that process foreign antigens) dysfunctional could affect seroconversion. Cancers, chemotherapy, underlying congenital immune deficiencies, liver diseases, might be on that list. MH