Efavirenz+Lamivudine+Tenofovir with Amoxicillin+Metronidazole

Question

Hi Dr,

I'm currently taking Efavirenz+Lamivudine+Tenofovir for my ART. I'm also taking atorvastatin 40mg for my cholesterol. I'm 31 yo. I recently had one of my molars removed which led to an infection. My dentists prescribed Amoxicillin (500mg) + Metronidazole (400mg) to be taken 3 times a day. Will this be alright?

Answer

Hello and thanks for posting.

There are no significant drug-drug interactions between your HIV medications and antibiotics.

Efavirenz tends to lower the levels of statin drugs like atorvastatin, so you may need higher doses of the later to achieve the desired effect.

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