It’s the early, panic-inducing days of a new virus. People who may have been exposed are quarantined. Americans are being asked to keep their distance from others, just in case someone has been exposed to the virus and doesn’t show signs of infection yet. There are scary reports of deaths from the virus, and uncertainty about how it spreads—and so, just to be safe, people are buying masks.
Sound familiar? In the early days of the AIDS epidemic, the panic was similar.
It may be hard to remember now, but there was a time between the discovery of the “gay cancer,” Kaposi’s sarcoma (KS), and the discovery of HIV, which destroys the immune system if left untreated and leads to AIDS-defining illnesses (KS among them).
But it was in those months and years when the most harmful myths about HIV that still persist were born: that you can get HIV from spit (2019, anyone?); that it was carried primarily in the air and saliva, and therefore people wanting to protect themselves from HIV shouldn’t share toilets or utensils with people living with the virus; that HIV was man-made; or that HIV itself doesn’t cause the virus and that something else does.
These beliefs led to dehumanizing treatment of people living with HIV, such as keeping them in quarantine. Loved ones were required to don gowns, masks, and gloves when they visited—visitors were even prohibited from touching their dying loved one. Medical professionals refused to treat people living with HIV, and sometimes roommates kicked their friends with AIDS out of their apartment, so afraid were Americans of HIV spreading.
It turned out that researchers identified HIV as the cause of AIDS in 1983, years after people had first developed AIDS. They also discovered that HIV was sexually transmitted, and that there was no reason to quarantine or avoid contact with people living with AIDS. But in that lag time, rumors spread that had homophobic and racist tinges to it.
Today, in 2020, we are watching a similar event happening again—and this time, the harmful rumors include a link between the novel coronavirus (2019-nCoV), which is causing an outbreak of severe respiratory symptoms in China, to HIV around the world.
Need-to-know information, expert guidance, and the latest news and analysis about how the novel coronavirus is affecting the HIV community.
Read MoreFirst, What We Know About Coronavirus vs. HIV
By Jan. 2, 2020, scientists had identified the cause of pneumonia in 41 people in Wuhan, China: a new version of the coronavirus. Coronaviruses are a group of respiratory viruses that have been recorded in cats, bats, camels, cattle, and humans. You might know one of the coronaviruses in the U.S.: the common cold.
The first of the more virulent strain of coronavirus in humans emerged in 2003, though, when severe acute respiratory syndrome (SARS) emerged in China. Another coronavirus, Middle East respiratory syndrome (MERS), was identified in humans in 2012. Now, there’s 2019-nCoV, short for “novel coronavirus, 2019.” It will get a proper name soon.
As of 10:43 a.m. ET on Feb. 5, 24,613 people worldwide have been diagnosed with 2019-nCoV, according to a 2019-nCoV tracker created by Johns Hopkins University. All but 221 of those have occurred on mainland China, most of those in Hubei province, where the outbreak started.
So far, 11 people have been diagnosed with the virus in the U.S., and Americans returning from China are being held in quarantine at March Air Reserve Base in Southern California. The idea is that, after 14 days, those in quarantine will either test positive and develop symptoms, or they will be free of the virus. Those who are sick will get treatment, and those who are 2019-nCoV negative will be allowed to leave.
Close to 500 people have died of the respiratory infection. But more than twice that, 1,028, have recovered from it. The rest are sick, and doctors are watching to see if they recover on their own or with treatments (which are all experimental). It’s only after the outbreak is contained that public health officials will be able to say how contagious the virus is.
2019-nCoV researchers have an advantage that early AIDS researchers didn’t have: They identified that the pneumonia cases were caused by a coronavirus, not by a bacteria or anything else. It’s a respiratory virus—unlike HIV, which spreads through sexual contact, blood, or breast milk when someone has a detectable viral load. The coronavirus is also heartier than HIV: HIV can’t live outside the human body for any period of time (which is why you should feel free to share utensils, hugs, and just about anything else with a person with HIV), but 2019-nCoV can survive on surfaces and spread through the air via coughs and sneezes.
What We Don’t Know About Coronavirus vs. HIV
It is early days yet with 2019-nCoV, and scientists and doctors are throwing a million ideas at the wall to figure out how to trace and treat the virus. And that opens the door to guesses, rumors, and outright conspiracy theories.
For instance, we don’t know how the virus got to humans. At first, public health officials thought it might have come from humans eating animals infected with the virus. There’s a very large food market in Wuhan, China, where the majority of people living with the virus live. (Related: Don’t let your fear of the virus translate to a fear of Chinese people.) People with HIV know this feeling all too well.) Now scientists think that it’s more likely that it spreads like any other cold: by person-to-person contact.
We don’t know how deadly this virus is, either. The early deaths indicate a virus with the potential to be very dangerous, but we don’t know if everyone who was exposed to the virus died, or if only the very sickest headed to the hospitals—and therefore were the only ones identified. It could be that it’s less deadly than it originally appeared—which seems more and more likely as the number of those who recover from the virus increasingly outpace those who have died. (A recent episode of This Podcast Will Kill You does a great job of explaining how scientists figure out how dangerous new viruses are.)
We also don’t know if people can transmit the virus unless they're already coughing, fatigued, and fevered, some of the most common symptoms of 2019-nCoV. Some viruses can spread even before achiness, sniffling, and fever appear. In SARS and MERS, that wasn’t the case: Someone had to be sick and coughing or sneezing out the virus, or accidentally wiping their saliva on surfaces. For now, it’s unclear whether someone without symptoms can still transmit 2019-nCoV.
This is despite an early case report in the New England Journal of Medicine that purported to find a Chinese businesswoman had transmitted the virus before she was sick. But that case report was based on faulty information, and has since been been called into question.
The New England Journal of Medicine has not yet responded to the new information.
No, 2019-nCoV Is Not Related to HIV
If the New England Journal of Medicine can be wrong, any scientist can be wrong. People like to think that scientists know The Truth. But the real truth is that science is hella messy, and you usually only get to the right answer after first eliminating all the wrong ones—publicly, in studies that are later debunked, retracted, or can’t be replicated.
And that means there can be a lot of false or misleading approaches published in the first frantic weeks of an outbreak.
So it was that a rumor emerged, based on a hastily published article sequencing 2019-nCoV’s DNA, that claimed to have discovered a link between 2019-nCoV and HIV.
Here’s how you know the claim was faulty: First, it's helpful to understand how scientific articles are published. Before most studies see the light of day (or Twitter mentions), they are usually reviewed by other scientists who are experts in the field to catch any faulty assumptions, data errors, or other mischaracterizations. Only after that—and everyone involved finds the results to be accurate and trustworthy—does it get the green light to be published. (Even then, this process doesn’t catch all errors).
But this paper (which we won’t link to—we don’t want to help it rank more highly on Google!) was published online before any peers reviewed it, on what’s called a pre-print server. That is to say, a place where researchers can post their findings online before experts review it for accuracy and a journal actually publishes it.
Second, as soon as scientific Twitter got wind of the study, the paper got peer reviewed to filth—that is to say, researchers pointed out all the problems with the assumption that HIV and 2019-nCoV were related at all.
Based on the content of my mentions, I feel like I need to further debunk crazy #nCoV2019 / HIV conspiracy preprint. This is a thread doing so. 1/9
— Trevor Bedford (@trvrb) February 1, 2020
To be clear, these observed insertions in spike protein are completely consistent with naturally occurring evolution in these viruses in bats. Spike has lots of evolutionary pressure and it mutates single bases as well as gains and loses sections across related bat viruses. 1/2
— Trevor Bedford (@trvrb) January 31, 2020
Just checked their results. The similarity is spurious. Out of 4 inserts they identify between NCov and SARS, 2 are found in bat coronavirus. Of the remaining two, only one is most similar to HIV, and is so short (6 AA) that the similarity is not higher than chance given database
— Silvana Konermann (@SKonermann) January 31, 2020
It’s much more likely, scientists said, that 2019-nCoV comes from bats, not HIV.
Third, the platform on which the study was published? It started adding warnings to all its 2019-nCoV studies: “A reminder: these are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.”
And finally, the authors themselves withdrew the article, telling Forbes, “It was not our intention to feed into the conspiracy theories and no such claims are made here.”
Those authors have not yet responded to TheBody’s request for comment.
The stark reality is that #nCoV2019 doesn't need to be engineered.. it exists in nature, like SARS, Ebola, HIV, bird flu etc. It doesn't have to escape from a lab, it's been liberated from it's natural host as a result of the wildlife trade.
— Hume Field (@HumeField) February 3, 2020
Fact is indeed stranger than fiction.. https://t.co/hr5UJn1Ypw
Even the use of the HIV drugs lopinavir and ritonavir (marketed under the brand name Kaletra) to try to control 2019-nCoV in Thailand doesn’t mean there’s a connection between the virus and HIV. After all, HIV medicines have been used to treat hepatitis B, Ebola, and other diseases; it's common for researchers to test out such drugs to see how well they might work against emerging viruses.
“Frankly, it’s so confusing because of the fact that they are sometimes using HIV drugs,” Carlos del Rio, M.D., chair of the Department of Global Health at Emory University’s Rollins School of Public Health, told TheBody. “But what we’re missing is the randomized controlled trials and other information to explain why HIV medications would work. What we have right now is anecdotal evidence that it works. Let’s not hang our hats on that.”
At any rate, those HIV drugs don’t seem to work consistently against the new coronavirus. It wasn’t found to work consistently against MERS, either.
Is Coronavirus a Concern for People Living With HIV?
Carlos del Rio has been treating people with HIV in Atlanta for decades. Though many of his patients have his cell phone number, none of them have asked him anything about the connection between HIV and 2019-nCoV.
The fact is, he said, people with HIV are more at risk for the common flu than 2019-nCoV. There have only been 11 cases of 2019-nCoV reported in the U.S., compared to more than 8,000 flu deaths so far this flu season. On Feb. 4, the New York Department of Health reported that one person under observation for potential infection with 2019-nCoV came back with a negative test. No one in the U.S. has died of the virus as of Feb. 5 at noon.
In order to be at risk of this virus, you have to have recently visited China, or you have to be in close contact with someone who has. And even then, the people who have suffered the worst with the virus are people who already have upper respiratory infections, he said.
“The one person who died from 2019-nCoV in the Philippines also had influenza B,” said del Rio. “You don’t want to have two upper respiratory tract infections. I don’t think the risk is so much for people with compromised immune systems, but for people with compromised lung systems.”
So the advice for people living with HIV concerned about coronavirus is the same it would be for any other respiratory infection: Take your HIV medicine, or talk to a provider or a friend with HIV about what’s getting in the way of your ability to take medicine. Get a flu shot. Wash your hands with soap and water. Cover your mouth when you cough.
“Be worried about the flu. Be worried about driving home tonight—that’s actually more dangerous,” del Rio said. “These are the things to keep your eye on.”
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Novel coronavirus: “About 2019 Novel Coronavirus (2019-nCoV),” Centers for Disease Control and Prevention. February 2020. cdc.gov/coronavirus/2019-ncov/about/index.html
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Coronaviruses: “Coronaviruses,” National Institute of Allergy and Infectious Diseases. January 2020. niaid.nih.gov/diseases-conditions/coronaviruses
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How coronavirus spreads: “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China,” The Lancet. January 24, 2020. thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext
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Authors withdrawing article: “No, The Wuhan Coronavirus Was Not Genetically Engineered To Put Pieces Of HIV In It,” Forbes. February 2, 2020. forbes.com/sites/victoriaforster/2020/02/02/no-coronavirus-was-not-bioengineered-to-put-pieces-of-hiv-in-it/#3c2f7c4656cb
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Using HIV drugs to fight MERS: “Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV,” Nature. 2020. nature.com/articles/s41467-019-13940-6.pdf
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The U.S. Food and Drug Administration and coronavirus: “FDA Takes Significant Step in Coronavirus Response Efforts, Issues Emergency Use Authorization for the First 2019 Novel Coronavirus Diagnostic,” FDA. February 4, 2020. fda.gov/news-events/press-announcements/fda-takes-significant-step-coronavirus-response-efforts-issues-emergency-use-authorization-first