Can having herpes affect and HIV test?

Question

I was wondering...i had an HIV test done last week and am still awaiting the results. I have HSV1 and have been having an outbreak for about a month, and have been, and still am on a high dose of acyclovir. Can any of this affect the outcome of the HIV test? also...how is it possible to get a false positive if you dont have HIV???

Answer

Neither an acute episode episode of herpes or herpes antiviral therapy should affect HIV testing results. Some people have antibodies that cross-react with components of the HIV antibody screening assay (ELISA) and cause false positive results. Because of this, a confirmatory test looking for specific antibodies to HIV proteins is always done to confirm HIV infection.