As of February 2017, elvitegravir is no longer sold in the United States. For questions about elvitegravir, contact Gilead Sciences, Inc. at 1-800-445-3235 and select option 2.
Brand Name: Vitekta
Other Name(s): EVG
Drug Class: Integrase Inhibitors
**Elvitegravir can cause changes in the immune system (immune reconstitution inflammatory syndrome [IRIS]).
While taking elvitegravir, it is important to keep all of your appointments with your health care provider.
What Is Elvitegravir?
Elvitegravir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults who are already taking or have taken HIV medicines before. Elvitegravir is always used in combination with other HIV medicines.
Elvitegravir belongs to a class (group) of HIV drugs called integrase inhibitors. Integrase inhibitors block an HIV enzyme called integrase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.
HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are taking HIV medicines, including elvitegravir, don't cut down on, skip, or stop taking them unless your health care provider tells you to.
What Should I Tell My Health Care Provider Before Taking Elvitegravir?
Before taking elvitegravir, tell your health care provider:
- If you are allergic to elvitegravir or any other medicines.
- If you have or have ever had liver problems.
- If you have any other medical conditions.
- If you are pregnant or plan to become pregnant. Whether elvitegravir can harm an unborn baby is unknown. Elvitegravir should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Talk to your health care provider about possible risks with taking elvitegravir when pregnant.
- If you are breastfeeding or plan to breastfeed. Do not breastfeed if you are infected with HIV or are taking elvitegravir.
- If you are using hormone-based birth control (such as pills, implants, or vaginal rings). Elvitegravir may make these forms of birth control less effective. Your health care provider can help you decide how to adjust your birth control while you are taking elvitegravir. For more information, view the AIDS_info_ HIV and Birth Control infographic.
- If you are taking cobicistat (brand name: Tybost) with a protease inhibitor or if you are taking other medicines that contain elvitegravir (for example, Striblid). Do not take elvitegravir if you are taking these medicines.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Elvitegravir may affect the way other medicines or products work, and other medicines or products may affect how elvitegravir works. Taking elvitegravir together with certain medicines or products may cause serious side effects.
How Should I Take Elvitegravir?
Elvitegravir (brand name: Vitekta) comes in tablet form in two strengths:
- 85-mg tablets.
- 150-mg tablets.
Take elvitegravir according to your health care provider's instructions.
Take elvitegravir with food. Elvitegravir must be taken with a protease inhibitor HIV medicine along with the HIV medicine ritonavir (brand name: Norvir) and with other HIV medicine(s). Talk to your health care provider about the HIV medicines you are taking.
If you take too much elvitegravir, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.
For more information on how to take elvitegravir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
What Should I Do if I Forget a Dose?
If you miss a dose of elvitegravir, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
What Side Effects Can Elvitegravir Cause?
Elvitegravir can cause serious side effects, including immune reconstitution inflammatory syndrome (IRIS). IRIS is a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection. (See the WARNING above.)
The most common side effect of elvitegravir is diarrhea.
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of elvitegravir. To learn more about possible side effects of elvitegravir, read the drug label or package insert or talk to your health care provider or pharmacist.
The AIDS_info_ fact sheet on HIV Medicines and Side Effects also includes information that may apply to elvitegravir.
You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at www.accessdata.fda.gov/scripts/medwatch/.
How Should Elvitegravir Be Stored?
- Store elvitegravir at room temperature below 86°F (30°C).
- Keep elvitegravir in the container that it came in.
- Do not use elvitegravir if the original seal over the bottle opening is broken or missing.
- Throw away elvitegravir that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep elvitegravir and all medicines out of reach of children.
Where Can I Find More Information About Elvitegravir?
More information about elvitegravir is available:
- The elvitegravir drug label, from DailyMed. The Patient Counseling Information section of the label includes information for people taking elvitegravir.
- Elvitegravir-related research studies, from the AIDS_info_ database of ClinicalTrials.gov study summaries.
- A list of FDA-approved HIV medicines, from AIDS_info_.
Gilead Sciences, Inc.
Main number: 800-445-3235
Patient assistance: 800-226-2056
The above Patient Version drug summary is based on the following FDA label(s): Tablet, film coated.