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HIV Drug-Drug Interactions
Overview
- Drug Interactions (April 28, 2008)
To read PDF, click here
From AIDS InfoNet
- Drug Interactions Among Antiretrovirals and Other Drugs: NNRTIs (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Among Antiretrovirals and Other Drugs: NRTIs (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Among Antiretrovirals and Other Drugs: PIs and Maraviroc (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drugs That Should Not Be Used With PI , NNRTI, or CCR5 Antagonist Antiretrovirals (PDF) (January 29, 2008)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Dosage Adjustments for ARV-ARV Drug Interactions (Adult Dosing) (July 2006)
From AIDS Education & Training Centers National Resource Center
- Antiretroviral Medications and Oral Contraceptive Agents (2006)
A chapter from Clinical Manual for Management of the HIV-Infected Adult.
From AIDS Education & Training Centers National Resource Center
- Interactions With HIV Medications: What HIV-Positive People Should Know (October 2005)
To read PDF, click here
From The Center for AIDS
- Creating a Friendly Environment for Your HIV Medications (Fall 2005)
How some HIV meds can interact with other meds, over-the-counter pills, supplements, etc.
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
- Drug Interactions and Anti-HIV Therapy (Summer 2005)
To read PDF, click here
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Pharmacokinetics: The Non-Nukes -- The Two Major Players (Winter 2004/2005)
Pharmacist Jean Lee explains how NNRTIs work, and how efavirenz and nevirapine might interact with other HIV meds.
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
- Pharmacokinetics: The Nukes -- Each One Works a Little Differently (Winter 2004/2005)
Pharmacist Patrick G. Clay explains how NRTIs work, and how they might interact with other HIV meds.
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
- Pharmacokinetics: The Protease Inhibitor Drugs (Winter 2004/2005)
Pharmacist James D. Scott explains how protease inhibitors work, and how they might interact with other HIV meds.
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
- Psychiatric and HIV Medication Interactions (January 2005)
A chart outlining known interactions between psychiatric medications and NRTIs, NNRTIs and protease inhibitors.
To read PDF, click here
In Infectious Diseases in Corrections Report, from Brown Medical School
- Drug Interactions Fact Sheet (August 2004)
An exhaustive list of drug interactions.
To read PDF, click here
From Project Inform
- Clinically Significant Drug Interactions Associated With Highly Active Antiretroviral Therapy (January 2004)
To read PDF, click here
In HEPP Report, from Brown Medical School
- Risky Cocktails (April 2003)
A chart of interactions between alcohol/recreational drugs and HIV antiretrovirals.
In Survival News, from AIDS Survival Project
- Methadone and HIV Medications: Drug Interactions (Winter 2002/2003)
To read PDF, click here
In STEP Perspective, from Seattle Treatment Education Project
- The Effects of Club Drugs on HAART (December 2002)
To read PDF, click here
In IAPAC Monthly, from International Association of Physicians in AIDS Care
- Pharmacology and Drug Interactions: A Progress Report (September 2002)
A report from the International AIDS Conference.
In Hopkins HIV Report
- Medicine Chest: Drugs and Food (July/August 2002)
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
- Drug Interactions: Ritonavir as PI Booster (July 2001)
From Project Inform
- Drug-Drug Interactions and Pharmacology (Spring 2001)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Antiretroviral Pharmacology: Issues and Management (Winter 2000)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- How to Avoid Adverse Reactions to HIV/AIDS Medications (June 1998)
In Positive Living, from AIDS Project Los Angeles
- Protease Inhibitor Drug Interactions: What Do Patients Need to Know? (August 27, 1997)
An edited transcript of a BETA Live! conference call broadcast.
From San Francisco AIDS Foundation
Drug Interaction Research
- Scientists Solve the Grapefruit Mystery (March 27, 2007)
In Washington Post
- Drug Monitoring and Pharmacology: More Mixes Nixed By Concentration Preoccupations (August 2004)
Highlights from a CROI 2004 post-conference workshop on drug-drug interactions.
In TAGline, from Treatment Action Group
- Tipranavir Reduces Concentrations of Other Protease Inhibitors (July 14, 2004)
In The XV International AIDS Conference, from The Body PRO
- Tenofovir and Abacavir Do Not Interact in Patients on Triple-Nucleoside Regimens (July 13, 2004)
In The XV International AIDS Conference, from The Body PRO
- Making Right Turns in the HIV Pharmacology Maze: 5th International Workshop on Clinical Pharmacology of HIV Therapy (July 2004)
Highlighted research on host factor relevance, new antiretrovirals and drug-drug interactions.
To read PDF, click here
In IAPAC Monthly, from International Association of Physicians in AIDS Care
- Dosing Agenerase + Kaletra -- Trying to Juggle, Walk and Chew Gum All at the Same Time (March/April 2004)
A study presented at CROI 2004 bolsters support for the use of therapeutic drug monitoring to customize dosing.
In Positively Aware, from Test Positive Aware Network
- Efavirenz May Reduce Blood Levels of Cholesterol Drugs (March/April 2004)
A study presented at CROI 2004 suggests an interaction between efavirenz and simvastatin (Zocor) or atorvastatin (Lipitor).
In Positively Aware, from Test Positive Aware Network
- A Look at Tenofovir Drug-Drug Interactions (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- No PK Interaction Seen Between FTC and AZT or Tenofovir (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- Pharmacokinetic Interactions of 908 (September 16, 2003)
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- No Interactions Between Tipranavir/Ritonavir and Efavirenz, Tenofovir and AZT (July 14, 2003)
In The 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment, from The Body PRO
- Progress in Pharmacology and Drug Interactions From the 10th CROI (May 2003)
In Hopkins HIV Report
- HIV-Positive Man Dies of Kidney Failure and Lactic Acidosis Due to Tenofovir/ddI Interaction (April 8, 2003)
From aidsmap.com
- Didanosine and Tenofovir DF Drug-Drug Interaction: Assessment of Didanosine Dose Reduction (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Lack of Interaction Between Stavudine Extended-Release Formulation and Tenofovir Disoproxil Fumarate (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Pharmacokinetic Parameters of Atazanavir/Ritonavir When Combined to Tenofovir in HIV Infected Patients With Multiple Treatment Failures: A Substudy of Puzzle2-ANRS 107 Trial (February 12, 2003)
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- New Questions About an Old Combination -- ddI + d4T (January 2003)
To read PDF, click here
In Project Inform Perspective, from Project Inform
- Tenofovir DF and Didanosine EC: Investigation of Pharmacokinetic Drug-Drug and Drug-Food Interactions (July 11, 2002)
In The XIV International AIDS Conference, from The Body PRO
- Polypharmacy Problems: Drug Interactions in the Multi-Drug Therapy of HIV Infection (February 6, 2002)
In The PRN Notebook
- Drug Interaction: Ritonavir and Fluticasone (November 2001)
Possible link found to Cushing's Syndrome.
In HIV Treatment ALERTS!, from The Center for AIDS
- Ingrown Toenails Still a Possible Side Effect (November 2001)
Indinavir-ritonavir interaction is possible culprit.
In HIV Treatment ALERTS!, from The Center for AIDS
- Lack of Clinically Relevant Drug-Drug Interactions Between Tenofovir DF and Efavirenz, Indinavir, Lamivudine and Lopinavir/Ritonavir in Healthy Subjects (October 29, 2001)
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO
- Minor Interaction Between Efavirenz and Saquinavir When Combined With Small Doses of Ritonavir in a QD Regimen (October 28, 2001)
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO
- Dealing With Drug Interactions (Summer/Autumn 2001)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Drug Interaction Research (2001)
From Forum for Collaborative HIV Research
Drug-Drug Interaction Tools
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