Treatment Action Group
Comparing Protease Combinations
May 1996
Reported maximum average reductions in plasma
RNA with selected protease inhibitor combinations
(in treament naive/experienced* individuals)
| | SQV | .6 log | S. Vella
|
| SQV(new formulation) | 1.5 log | Roche
|
| RTV | 1.2-1.9 log | Abbott
|
| IDV | 1.2-2.0 log | Merck
|
| NFV | 1.5 log | Markowitz
|
| SQV+AZT | 1.0 log | S. Vella
|
| SQV+ddC | .6 log | Roche NV*
|
| SQV+AZT+ddC | .8 log | ACTG 229*
|
| RTV+AZT | 1.2 log | Abbott
|
| RTV+AZT+ddC | 2.0-2.5 log | Leibowich
|
| IDV+AZT | 1.4-1.5 log | Merck
|
| IDV+AZT+ddl | 2.9 log | Merck
|
| IDV+AZT3TC | >2.0 log | Merck 035*
|
| NFV+d4T | 2.4-2.6 log | Chapman
|
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Treatment Action Group.
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