Question:
Dr's, I am having terrible gastrointestinal problems with, the ratonavir and saquinavir combination I am taking. My major
complaints are stomach cramps and extreme flatulence. I am taking three physyme capsules daily and cannot keep up with
the problem. I look very pregnant. Is there an oral medication more effective I could take or perhaps a special diet? I
cannot wear any of my clothes and it has created a major problem for me. Did you hear anything about how to ease the
side effects at the conference? I'll take any suggestion you might have to offer. Thanks Terry
Dr. Torres' Response:
It sounds like the gastrointestinal side effects of this combination are
intolerable; I would recommend using the lowest recommended dose of both
drugs (400 mg twice daily) if the gi problems persist you should strongly
consider another combination regimen.
Ramon Torres, MD
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