The Body: The Complete HIV/AIDS Resource Follow Us Follow Us on Facebook Follow Us on Twitter 
Professionals >> Visit The Body PROThe Body en Espanol
  • Email Email
  • Glossary Glossary

Prezista (Darunavir)

The Details

Prezista (darunavir or DRV; previously known as TMC114) is a protease inhibitor used to treat HIV/AIDS. It is approved by the U.S. FDA for the treatment of HIV infection in adults and children 3 years of age and older. It is listed in the HHS HIV treatment guidelines as part of a recommended regimen for people starting HIV treatment for the first time, when taken in combination with Norvir and Truvada.


Adult single dose: Take 800 mg with Norvir 100 mg once daily. Tablets come in the following strengths: 75 mg, 150 mg, 600 mg and 800 mg.
For those with at least one darunavir resistance associated substitution: Take one 600-mg tablet with Norvir 100 mg twice daily.


  • Take with food.
  • Always take Prezista in combination with the anti-HIV medicine Norvir and other anti-HIV medicines.
  • Women should not breastfeed while on Prezista.
  • Not recommended for use in patients with severe hepatic impairment.
The Basics

  • Email Email
  • Glossary Glossary

The content on this page is free of advertiser influence and was produced by our editorial team. See our advertising policy.