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Prezista (Darunavir, TMC114)

The Basics | News | Research

See also: Drug Interactions | Medication Side Effects

Show Archived (Historical) Articles

Brand Name:	Prezista
Generic Name:	darunavir, TMC114
Adult Single Dose:	Two 300 mg tablets twice daily taken with ritonavir 100 mg twice daily.
Food & Liquid Restrictions:	Take with food.
Drug Class:	PI

The Basics

An Overview of Prezista (Darunavir, TMC114) (Regularly Updated)
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From U.S. National Institutes of Health
Prezista (March/April 2009)
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In Positively Aware, from Test Positive Aware Network
Darunavir (Prezista) (March 17, 2009)
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From AIDS InfoNet
Patient Information About Prezista (Darunavir, TMC114) (PDF) (December 2008)
From Tibotec Therapeutics
Prezista (Darunavir, TMC-114) (September 28, 2007)
Basic information on dosing schedules and side effects.
From U.S. Department of Veterans Affairs
An Interview With Cal Cohen, M.D., a Lead Investigator of the Darunavir (TMC114, Prezista) POWER Trials (June 28, 2006)
Dr. Cohen discusses TMC114's uses, adverse effects and other considerations.
Prezista Approval (June 23, 2006)
From U.S. Food and Drug Administration

News

Prezista Now Available for Pediatric Patients Six Years of Age and Older as Part of HIV Combination Therapy (February 11, 2009)
From Tibotec Therapeutics
New 75 mg Prezista Tablet and Corresponding Pediatric Dosing Information Approved (December 18, 2008)
From U.S. Food and Drug Administration
HIV/AIDS Update - Important information about Prezista (darunavir) (October 22, 2008)
From U.S. Food and Drug Administration
Updates to Prezista (Darunavir) Tablets Labeling (March 11, 2008)
From U.S. Food and Drug Administration
"Dear Healthcare Professional" Letter: New Prescribing Information for Prezista (Darunavir) (March 2008)
Labeling has been updated to include warnings regarding hepatotoxicity.
From Tibotec Therapeutics
New 600-mg Tablet Strength for Prezista (Darunavir) (February 26, 2008)
From U.S. Food and Drug Administration
A Drug Pricing Victory: Tibotec Prices Prezista at Far Below Cost of Reyataz, Fuzeon (June 30, 2006)

Research

Adding Etravirine to Prezista Improves Anti-HIV Activity, Studies Show (July 6, 2007)
From aidsmap.com
Darunavir Superior to Lopinavir in 48-Week Study in Treatment-Experienced Patients (July 6, 2007)
From aidsmap.com
GRACE Under Pressure (December 2006)
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In TAGline, from Treatment Action Group
48-Week TMC114 + Ritonavir Data Set New Bar for Efficacy in Triple-Class-Experienced Patients (August 15, 2006)
In XVI International AIDS Conference

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