Structured HIV/AIDS Treatment Interruptions: Research/Trial Results
- Treatment Interruption Revisited (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Treatment Interruption Uncovers HIV's Attack on the Kidneys (February 2009)
To read PDF, click here
In Treatment Update, from Canadian AIDS Treatment Information Exchange
- Markers of Inflammation and Blood-Clotting Tied to Hazards of Intermittent HIV Treatment (October 21, 2008)
From National Institute of Allergy and Infectious Diseases
- Markers of Inflammation and Blood-Clotting Tied to Hazards of Intermittent HIV Treatment (October 21, 2008)
From U.S. National Institutes of Health
- Interleukin-2 Ineffective in Maintaining Baseline CD4+ Cell Count During Treatment Interruption (February 6, 2008)
From The Body PRO
- Resuming Treatment Partly Restores Health of Patients in SMART Study (February 3, 2008)
In 15th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Are Previous Treatment Interruptions Associated With Higher Viral Rebound Rates in Patients With Viral Suppression? (January 30, 2008)
In AIDS
- Dutch Study Finds STIs Safe for Some (October 2007)
To read PDF, click here
In Project Inform Perspective, from Project Inform
- TILT: A Look at the Role of Interleukin-2 in Treatment Interruption Leans Toward the Negative (February 28, 2007)
In Exclusive Coverage of the 14th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- CD4+ Count-Guided Interruption of Antiretroviral Treatment (November 30, 2006)
In New England Journal of Medicine
- SMART & Staccato: Two CD4-Guided Treatment Interruption Trials With Contradictory Results (August 17, 2006)
In XVI International AIDS Conference
- Staccato Study Suggests That Some CD4-Guided Treatment Interruptions Can be Safe (August 8, 2006)
In Time
- Treatment Interruptions: SMART or Stupid? (Spring 2006)
An in-depth look at the data behind the SMART study -- and what lessons, if any, can be learned from the results.
To read PDF, click here
In ACRIA Update, from AIDS Community Research Initiative of America
- Intermittent Treatment-Interruption Arm of Major African Study Is Halted (March 15, 2006)
From aidsmap.com
- Community Sign-On Letter: Continue the SMART Trial (January 27, 2006)
From The Center for AIDS
- International HIV/AIDS Trial Finds Continuous Antiretroviral Therapy Superior to Episodic Therapy (January 18, 2006)
The massive, international SMART trial is abruptly cancelled due to a twofold greater risk of progression to AIDS among people taking periodic treatment interruptions.
To read PDF, click here
From U.S. National Institute of Allergy and Infectious Diseases
- Treatment Action Group Statement on the Termination of the SMART Study (January 18, 2006)
Many other types of HIV treatment interruptions may still have a benefit -- it is still too early to call them a failed strategy, the group says.
To read PDF, click here
From Treatment Action Group
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