Specific HIV/AIDS Medication Interactions
General
- ARV Alert (Regularly Updated)
Periodic updates on newly announced interactions involving HIV medications; each update features a brief synopsis of the interaction, as well as a chart outlining key information.
From HIV InSite
- Information for Health Care Professionals: Update to the Labeling of Clopidogrel Bisulfate (Marketed as Plavix) to Alert Health Care Professionals About a Drug Interaction With Omeprazole (Marketed as Prilosec and Prilosec OTC) (November 17, 2009)
From U.S. Food and Drug Administration
- Sustiva + Ginkgo: Possible Recipe for Resistance, Doctors Report (May 21, 2009)
From aidsmap.com
- Patient Information About Reyataz (Atazanavir) (PDF) (April 2009)
From Bristol-Myers Squibb Company
- Warnings About Taking Reyataz With Sustiva, Viramune, Oral Contraceptives (August 21, 2008)
From U.S. Food and Drug Administration
- Acid-Reducing Agents Reduce Atazanavir Drug Levels but Not Lopinavir/Ritonavir Levels (February 7, 2006)
In The 13th Conference on Retroviruses and Opportunistic Infections
- French Study Questions Interaction Between Atazanavir and Antacids (October 24, 2005)
[Archived Article]
From aidsmap.com
- ddI + Ribavirin May Cause Mitochondrial Toxicity (September 1, 2005)
In Journal of Acquired Immune Deficiency Syndromes
- Efavirenz Reduces Plasma Levels of Popular Statins (July/August 2005)
[Archived Article]
From The Body PRO
- Antacids and HIV Medications (May/June 2005)
[Archived Article]
Over-the-counter antacids like Mylanta, Rolaids and Tums can decrease blood levels of some HIV meds.
In Survival News, from AIDS Survival Project
- Notice of Important New Drug Interactions With Norvir, Kaletra (March 30, 2005)
[Archived Article]
New interactions noted with fluticasone (a component of Flonase nasal spray) and trazodone (Desyrel, an antidepressant).
From U.S. Food and Drug Administration
- Drug Interaction Warning: Saquinavir/Ritonavir and Rifampin (Rifampicin, Rifadin, Rimactane, Rofact) (February 8, 2005)
[Archived Article]
To read PDF, click here
From U.S. Food and Drug Administration
- Don't Combine Fosamprenavir and Lopinavir/Ritonavir (February/March 2005)
[Archived Article]
From The Body PRO
- Do Not Combine Reyataz and Prilosec: News Summary (December 31, 2004)
[Archived Article]
In AIDS Treatment News, from AIDS Treatment News
- Atazanavir, With or Without Ritonavir, Should Not Be Coadministered With Proton Pump Inhibitors (December 20, 2004)
From U.S. Food and Drug Administration
- Warning Against Using Erythromycin (Even Orally) While Using Protease Inhibitors or Certain Other Drugs (October 26, 2004)
[Archived Article]
A study finds an increased risk of sudden death from cardiac causes.
In AIDS Treatment News, from AIDS Treatment News
- ddI + Tenofovir Combination Linked to Higher Pancreatitis Risk (October 2004)
[Archived Article]
Quick recap of a report in The Lancet.
In HIV Treatment ALERTS!, from The Center for AIDS
- Interaction Reported Between Grapefruit Juice and Statins (October 2004)
[Archived Article]
This interaction may also worsen other interactions between statins and HIV medications.
In HIV Treatment ALERTS!, from The Center for AIDS
- News on Developing Drugs and Drug Interactions (September/October 2004)
[Archived Article]
Updates on tipranavir, GS 9005 and the interaction between ddI and tenofovir.
In GMHC Treatment Issues, from Gay Men's Health Crisis
- Genetics Influence Response to HAART and Incidence of Pancreatitis, Studies Show (August 3, 2004)
[Archived Article]
From aidsmap.com
- Changes to Labeling for Desyrel (Trazodone Hydrochloride) Tablets (PDF) (May 2004)
[Archived Article]
A "Dear Healthcare Professional" letter on potential interactions between this antidepressant and CYP3A4 inhibitors such as indinavir and ritonavir.
From U.S. Food and Drug Administration
- Non-Antiretroviral Medication-Related Adverse Events During Treatment of HIV-Related Infections and Complications (May 2004)
[Archived Article]
From HIV InSite
- Atazanavir (Reyataz): New Recommendations if Combined With Tenofovir (Viread) -- and Warning on Viagra, Cialis, and Levitra (March 26, 2004)
[Archived Article]
New warnings on drug-drug interactions are noted in the prescribing information for atazanavir.
In AIDS Treatment News, from AIDS Treatment News
- Atazanavir/Tenofovir Combo Should Be Boosted With Ritonavir (August 8, 2003)
From U.S. Food and Drug Administration
- HIV-Positive Man Dies of Kidney Failure and Lactic Acidosis Due to Tenofovir/ddI Interaction (April 8, 2003)
[Archived Article]
From aidsmap.com
- Herbs, Supplements and HIV: Drug Interactions (April 2003)
[Archived Article]
To read PDF, click here
From Project Inform
- Tenofovir DF and Didanosine EC: Investigation of Pharmacokinetic Drug-Drug and Drug-Food Interactions (November 21, 2002)
[Archived Article]
In The 6th International Congress on Drug Therapy in HIV Infection, from The Body PRO
- Intracellular Metabolism of AZT Leads to the Production of Significant Levels of d4T Triphosphate in HIV Infected Patients (November 19, 2002)
[Archived Article]
In The 6th International Congress on Drug Therapy in HIV Infection, from The Body PRO
- New Safety Information -- Viread Co-Administration With Videx (September 30, 2002)
[Archived Article]
From U.S. Food and Drug Administration
- Viread-Videx EC Drug Interactions -- What's a Person to Do? (Fall 2002)
[Archived Article]
To read PDF, click here
In STEP Perspective, from Seattle Treatment Education Project
- New Safety Information for Videx (Didanosine, ddI) Used With Ribavirin (September 25, 2002)
[Archived Article]
From U.S. Food and Drug Administration
- FDA Bits: 3TC, Amprenavir and Nandrolone (September 2002)
[Archived Article]
Once-a-day dosing for 3TC (Epivir) approved; new interaction warnings for amprenavir (Agenerase); nandrolone decanoate returns to the U.S. market.
In HIV Treatment ALERTS!, from The Center for AIDS
- Drug Interactions Need More Attention (January 25, 2002)
[Archived Article]
To read PDF, click here
In AIDS Treatment News, from AIDS Treatment News
- Caution With Nelfinavir and Some Lipid-Lowering Drugs (November 21, 2001)
[Archived Article]
From Canadian AIDS Treatment Information Exchange
- Bizarre Side Effects From an Interaction Between Nevirapine and Clarithromycin (August 17, 2001)
[Archived Article]
From Canadian AIDS Treatment Information Exchange
- Women and Pharmacology (March 2001)
[Archived Article]
To read PDF, click here
In Project Inform Perspective, from Project Inform
- Risk of Interactions Between Zyban & HAART (March 5, 2001)
[Archived Article]
From aidsmap.com
- Drug Transporter, Drug Concentrations, and Drug Interactions (March 1, 2001)
[Archived Article]
In Hopkins HIV Report
- Drug Interactions of Protease Inhibitors and Psychiatric Medications (January 2001)
[Archived Article]
In Survival News, from AIDS Survival Project
- Caution Advised When Using Cipro With Methadone (December 20, 2000)
[Archived Article]
From Canadian AIDS Treatment Information Exchange
- Methadone Interferes With Some Formulations of ddI (September 8, 2000)
[Archived Article]
From Canadian AIDS Treatment Information Exchange
- Protease Inhibitors Interact With Some Sleeping Pills (August 31, 2000)
[Archived Article]
From Canadian AIDS Treatment Information Exchange
- Ritonavir and PI-Boosting: Using Drug/Drug Interactions to Our Advantage (July 14, 2000)
[Archived Article]
In STEP Ezine, from Seattle Treatment Education Project
- Selected Highlights From the 7th CROI: Drug Interaction and Side Effect Studies (Spring 2000)
[Archived Article]
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- What You Should Know About Mixing Cocktails (Spring 2000)
[Archived Article]
In STEP Perspective, from Seattle Treatment Education Project
- Drug Interaction and the Anti-HIV Drug Emivirine (Coactinon) (December 1999)
[Archived Article]
From Project Inform
- Drug Interactions Studied at ICAAC (November 1999)
[Archived Article]
In Positive Living, from AIDS Project Los Angeles
- FDA Strengthens Warning Label for Propulsid (June 29, 1998)
[Archived Article]
Heartburn drug may interact with protease inhibitors.
From U.S. Food and Drug Administration
- Efavirenz (Sustiva, DMP 266) and Saquinavir (Fortovase) Combination: Pharmacologic Interaction (June 5, 1998)
[Archived Article]
From AIDS Treatment News
- Drug Interactions Associated With Protease Inhibitors (May 1998)
[Archived Article]
In Positive Living, from AIDS Project Los Angeles
- Drug Interactions: Another Complication in HIV Care (April 1998)
[Archived Article]
In Positive Living, from AIDS Project Los Angeles
- Drug Interactions: Resources for Patients and Professionals (March 6, 1998)
[Archived Article]
In AIDS Treatment News, from AIDS Treatment News
- Drugs That May Interact With Protease Inhibitors via CYP3A4 Metabolism (December 18, 1997)
[Archived Article]
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Effects of Protease Inhibitors and Other Commonly Used Medications as Determined by Drug Interaction Studies (December 18, 1997)
[Archived Article]
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Medications That Should Not Be Used With Protease Inhibitors (December 18, 1997)
[Archived Article]
In Protease Inhibitors Backgrounder, from U.S. Food and Drug Administration
- Protease Inhibitor Drug Interactions: What Do Patients Need to Know? (August 27, 1997)
[Archived Article]
An edited transcript of a BETA Live! conference call broadcast.
From San Francisco AIDS Foundation
- Book Review of "Powers and Moore's Food-Medications Interactions" (May 1997)
[Archived Article]
In Journal of the International Association of Physicians in AIDS Care, from International Association of Physicians in AIDS Care
- Medications Contraindicated With the Use of Ritonavir (April 3, 1996)
[Archived Article]
In TAGline, from Treatment Action Group
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