HIV Drug-Drug Interactions
Overview
- Interactions Between NNRTIs, MVC, RAL, and PIs (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Between CCR5 Antagonist, Integrase Inhibitor and Other Drugs (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Between NNRTIs and Other Drugs (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Between NRTIs and Other Drugs (Including ARV Agents) (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions Between PIs and Other Drugs (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drugs That Should Not Be Used With PI, NNRTI, or CCR5 Antagonist (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Interactions Among PIs (PDF) (January 10, 2011)
An excerpt from the official U.S. HIV treatment guidelines for adults and adolescents. For the full guidelines, click here (PDF).
From AIDSinfo
- Drug Interactions (November 14, 2010)
To read PDF, click here.
From AIDS InfoNet
- Drug Interactions and HIV/AIDS (August 2010)
From The Well Project
- Labeling for Protease Inhibitors Updated With New Info on Drug-Drug Interactions (April 27, 2010)
From U.S. Food and Drug Administration
- Dosage Adjustments for ARV-ARV Drug Interactions (Adult Dosing) (July 2006)
[Archived Article]
From AIDS Education & Training Centers National Resource Center
- Antiretroviral Medications and Oral Contraceptive Agents (2006)
[Archived Article]
A chapter from Clinical Manual for Management of the HIV-Infected Adult.
From AIDS Education & Training Centers National Resource Center
- Interactions With HIV Medications: What HIV-Positive People Should Know (October 2005)
[Archived Article]
To read PDF, click here.
From The Center for AIDS
- Creating a Friendly Environment for Your HIV Medications (Fall 2005)
[Archived Article]
How some HIV meds can interact with other meds, over-the-counter pills, supplements, etc.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Drug Interactions and Anti-HIV Therapy (Summer 2005)
[Archived Article]
To read PDF, click here.
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Pharmacokinetics: The Non-Nukes -- The Two Major Players (Winter 2004/2005)
[Archived Article]
Pharmacist Jean Lee explains how NNRTIs work, and how efavirenz and nevirapine might interact with other HIV meds.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Pharmacokinetics: The Protease Inhibitor Drugs (Winter 2004/2005)
[Archived Article]
Pharmacist James D. Scott explains how protease inhibitors work, and how they might interact with other HIV meds.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Pharmacokinetics: The Nukes -- Each One Works a Little Differently (Winter 2004/2005)
[Archived Article]
Pharmacist Patrick G. Clay explains how NRTIs work, and how they might interact with other HIV meds.
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Psychiatric and HIV Medication Interactions (January 2005)
[Archived Article]
A chart outlining known interactions between psychiatric medications and NRTIs, NNRTIs and protease inhibitors.
To read PDF, click here.
In Infectious Diseases in Corrections Report, from Brown Medical School
- Drug Interactions Fact Sheet (August 2004)
[Archived Article]
An exhaustive list of drug interactions.
To read PDF, click here.
From Project Inform
- Clinically Significant Drug Interactions Associated With Highly Active Antiretroviral Therapy (January 2004)
[Archived Article]
To read PDF, click here.
In HEPP Report, from Brown Medical School
- Pharmacokinetics (July 2003)
Written with a focus on women.
From The Well Project
- Risky Cocktails (April 2003)
[Archived Article]
A chart of interactions between alcohol/recreational drugs and HIV antiretrovirals.
In Survival News, from AIDS Survival Project
- The Effects of Club Drugs on HAART (December 2002)
[Archived Article]
To read PDF, click here.
In IAPAC Monthly, from International Association of Physicians in AIDS Care
- Methadone and HIV Medications: Drug Interactions (Winter 2002/2003)
[Archived Article]
To read PDF, click here.
In STEP Perspective, from Seattle Treatment Education Project
- Pharmacology and Drug Interactions: A Progress Report (September 2002)
[Archived Article]
A report from the International AIDS Conference.
In Hopkins HIV Report
- Medicine Chest: Drugs and Food (July/August 2002)
[Archived Article]
To read PDF, click here.
In Positively Aware, from Test Positive Aware Network
- Drug Interactions: Ritonavir as PI Booster (July 2001)
[Archived Article]
From Project Inform
- Drug-Drug Interactions and Pharmacology (Spring 2001)
[Archived Article]
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Antiretroviral Pharmacology: Issues and Management (Winter 2000)
[Archived Article]
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- How to Avoid Adverse Reactions to HIV/AIDS Medications (June 1998)
[Archived Article]
In Positive Living, from AIDS Project Los Angeles
- Protease Inhibitor Drug Interactions: What Do Patients Need to Know? (August 27, 1997)
[Archived Article]
An edited transcript of a BETA Live! conference call broadcast.
From San Francisco AIDS Foundation
Drug Interaction Research
- One Third on First-Line Antiretrovirals Have Clinically Significant Drug Interactions (September 13, 2010)
From National AIDS Treatment Advocacy Project
- Scientists Solve the Grapefruit Mystery (March 27, 2007)
In Washington Post
- Drug Monitoring and Pharmacology: More Mixes Nixed By Concentration Preoccupations (August 2004)
[Archived Article]
Highlights from a CROI 2004 post-conference workshop on drug-drug interactions.
In TAGline, from Treatment Action Group
- Tipranavir Reduces Concentrations of Other Protease Inhibitors (July 14, 2004)
[Archived Article]
In The XV International AIDS Conference, from The Body PRO
- Tenofovir and Abacavir Do Not Interact in Patients on Triple-Nucleoside Regimens (July 13, 2004)
[Archived Article]
In The XV International AIDS Conference, from The Body PRO
- Making Right Turns in the HIV Pharmacology Maze: 5th International Workshop on Clinical Pharmacology of HIV Therapy (July 2004)
[Archived Article]
Highlighted research on host factor relevance, new antiretrovirals and drug-drug interactions.
To read PDF, click here.
In IAPAC Monthly, from International Association of Physicians in AIDS Care
- Efavirenz May Reduce Blood Levels of Cholesterol Drugs (March/April 2004)
[Archived Article]
A study presented at CROI 2004 suggests an interaction between efavirenz and simvastatin (Zocor) or atorvastatin (Lipitor).
In Positively Aware, from Test Positive Aware Network
- Dosing Agenerase + Kaletra -- Trying to Juggle, Walk and Chew Gum All at the Same Time (March/April 2004)
[Archived Article]
A study presented at CROI 2004 bolsters support for the use of therapeutic drug monitoring to customize dosing.
In Positively Aware, from Test Positive Aware Network
- Pharmacokinetic Interactions of 908 (September 16, 2003)
[Archived Article]
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- No PK Interaction Seen Between FTC and AZT or Tenofovir (September 16, 2003)
[Archived Article]
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- A Look at Tenofovir Drug-Drug Interactions (September 16, 2003)
[Archived Article]
In The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, from The Body PRO
- No Interactions Between Tipranavir/Ritonavir and Efavirenz, Tenofovir and AZT (July 14, 2003)
[Archived Article]
In The 2nd International AIDS Society Conference on HIV Pathogenesis and Treatment, from The Body PRO
- Progress in Pharmacology and Drug Interactions From the 10th CROI (May 2003)
[Archived Article]
In Hopkins HIV Report
- HIV-Positive Man Dies of Kidney Failure and Lactic Acidosis Due to Tenofovir/ddI Interaction (April 8, 2003)
[Archived Article]
From aidsmap.com
- Lack of Interaction Between Stavudine Extended-Release Formulation and Tenofovir Disoproxil Fumarate (February 12, 2003)
[Archived Article]
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Pharmacokinetic Parameters of Atazanavir/Ritonavir When Combined to Tenofovir in HIV Infected Patients With Multiple Treatment Failures: A Substudy of Puzzle2-ANRS 107 Trial (February 12, 2003)
[Archived Article]
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Didanosine and Tenofovir DF Drug-Drug Interaction: Assessment of Didanosine Dose Reduction (February 12, 2003)
[Archived Article]
In The 10th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- New Questions About an Old Combination -- ddI + d4T (January 2003)
[Archived Article]
To read PDF, click here.
In Project Inform Perspective, from Project Inform
- Tenofovir DF and Didanosine EC: Investigation of Pharmacokinetic Drug-Drug and Drug-Food Interactions (July 11, 2002)
[Archived Article]
In The XIV International AIDS Conference, from The Body PRO
- Polypharmacy Problems: Drug Interactions in the Multi-Drug Therapy of HIV Infection (February 6, 2002)
[Archived Article]
In The PRN Notebook
- Ingrown Toenails Still a Possible Side Effect (November 2001)
[Archived Article]
Indinavir-ritonavir interaction is possible culprit.
In HIV Treatment ALERTS!, from The Center for AIDS
- Drug Interaction: Ritonavir and Fluticasone (November 2001)
[Archived Article]
Possible link found to Cushing's Syndrome.
In HIV Treatment ALERTS!, from The Center for AIDS
- Lack of Clinically Relevant Drug-Drug Interactions Between Tenofovir DF and Efavirenz, Indinavir, Lamivudine and Lopinavir/Ritonavir in Healthy Subjects (October 29, 2001)
[Archived Article]
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO
- Minor Interaction Between Efavirenz and Saquinavir When Combined With Small Doses of Ritonavir in a QD Regimen (October 28, 2001)
[Archived Article]
In 8th European Conference on Clinical Aspects and Treatment of HIV-Infection, from The Body PRO
- Dealing With Drug Interactions (Summer/Autumn 2001)
[Archived Article]
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Drug Interaction Research (2001)
[Archived Article]
From Forum for Collaborative HIV Research
Drug-Drug Interaction Tools
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Glossary
