Heart Disease & HIV/AIDS: Research
- Serious Non-AIDS Health Problems (Especially Heart Problems) Appear Less Likely With Truvada Than Epzicom, But Low Bone Mineral Density Is More Likely, Switch Study Finds (October 20, 2009)
In Clinical Infectious Diseases
- Crestor May Top Pravachol as Lipid Buster Among HIVers on Norvir-Boosted Protease Inhibitors (October 15, 2009)
In AIDS
- Untreated HIV Associated With Less-"Elastic" Arteries, Raising Heart Disease Risk, Study Finds (September 3, 2009)
From The Body
- Long-Term HIV Treatment May Reduce Risk for Coronary Atherosclerosis, Pitt Study Finds (August 4, 2009)
From University of Pittsburgh
- Nevirapine Sports Better Lipid Profile Than Atazanavir, Study Suggests (July 20, 2009)
Patients taking nevirapine may have a lower risk of developing cardiovascular disease than those taking ritonavir-boosted atazanavir, according to a 569-patient study by European researchers. The study found that although nevirapine's efficacy was non-inferior to that of atazanavir, nevirapine appeared to have a more favorable lipid profile.
In Kaiser Daily U.S. HIV/AIDS Report, from Henry J. Kaiser Family Foundation
- HIV, HAART, and the Heart (July 14, 2009)
From amfAR, The Foundation for AIDS Research
- HIV Itself Linked to Possible Heart Risk, Even Among Nonprogressors, Study Finds (June 3, 2009)
From The Body
- Leptin Injections May Help HIVers With Lipoatrophy, Other Metabolic Problems, According to Small Study (April 2009)
The full text of a study published in the Journal of Clinical Endocrinology & Metabolism.
From National AIDS Treatment Advocacy Project
- Whither Recombinant Human Leptin Treatment for HIV-Associated Lipoatrophy and the Metabolic Syndrome? (April 2009)
Christos Mantzoros, M.D., an associate professor at Harvard Medical School, offers his take on whether there's a future for leptin replacement as a treatment for metabolic complications in people with HIV. (Editorial originally published in the Journal of Clinical Endocrinology & Metabolism.)
From National AIDS Treatment Advocacy Project
- Association of C-Reactive Protein and HIV Infection With Acute Myocardial Infarction (April 21, 2009)
In Journal of Acquired Immune Deficiency Syndromes
- Starting HIV Therapy May Improve Some Markers of Heart Health, Small Study Finds (April 21, 2009)
These new findings won't necessarily clear up the still-obscure relationship between HIV, HIV meds and heart disease, but they do support the idea that starting HIV treatment may not automatically jack up your cardiovascular risk.
From aidsmap.com
- HIV Type 1 Infection, and Not Short-Term HAART, Induces Endothelial Dysfunction (April 13, 2009)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- High Lipids May Be Harder to Treat for HIV-Positive People, Study Says (March 16, 2009)
Excerpt of the study, "Response to Newly Prescribed Lipid-Lowering Therapy in Patients With and Without HIV Infection," published in the Annals of Internal Medicine on March 3, 2009.
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- CROI 2009 Highlights: A Review of Cardiovascular Disease and HIV (March 15, 2009)
An interview with David Wohl, M.D.
In The 16th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Cardiovascular Risk (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
- Diabetes Mellitus, Preexisting Coronary Heart Disease, and the Risk of Subsequent Coronary Heart Disease Events in Patients Infected with Human Immunodeficiency Virus: the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D Study). (February 13, 2009)
In Circulation
- HIV on Par With Smoking, Diabetes as Risk Factor for Atherosclerosis, Large Study Finds (February 11, 2009)
Carl Grunfeld, M.D., Ph.D., and Colette Smith present new findings from a pair of massive studies that explore factors associated with cardiovascular risk in HIV-infected patients. Dr. Grunfeld's data suggest that HIV itself is a major risk factor for atherosclerosis -- a far greater risk, in fact, than any that may be posed by the use of antiretrovirals.
In The 16th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Jens Lundgren, M.D., Discusses New Findings Regarding MI Risk of Specific Antiretrovirals (February 9, 2009)
The latest data from D:A:D indicate that lopinavir/ritonavir does increase myocardial infarction risk, but efavirenz, nevirapine and tenofovir do not. In this interview, Jens Lundgren, M.D., and HIV advocate Jeff Berry take part in a fascinating discussion on the new findings and their possible underlying causes.
In The 16th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Carotid Intima-Media Thickness and Arterial Stiffness in HIV-Infected Ptients: the Role of HIV, Antiretroviral Therapy, and Lipodystrophy (February 1, 2009)
In Journal of Acquired Immune Deficiency Syndromes
- Illnesses Associated With Aging May Strike HIVers Earlier, Study Suggests (January 26, 2009)
From National AIDS Treatment Advocacy Project
- Abacavir Treatment Doesn't Cause Changes in Biomarkers Linked to Heart Attack, Suggests Small Study (December 2, 2008)
From aidsmap.com
- Surprising Rate of Serious Heart Condition Found in Those on HAART (December 2008)
To read PDF, click here
In Project Inform Perspective, from Project Inform
- Australia: AIDS Drugs Trigger Inflammation Linked to Diabetes, Study Says (November 18, 2008)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
- Markers of Inflammation and Blood-Clotting Tied to Hazards of Intermittent HIV Treatment (October 21, 2008)
From U.S. National Institutes of Health
- Markers of Inflammation and Blood-Clotting Tied to Hazards of Intermittent HIV Treatment (October 21, 2008)
From National Institute of Allergy and Infectious Diseases
- Cardiovascular Manifestations in Human Immunodeficiency Virus-Infected Patients (September 1, 2008)
In The American Journal of Cardiology
- Low CD4 Cell Count, But Not HIV Treatment, Increases Risk of Hardening of the Arteries (August 19, 2008)
From aidsmap.com
- Screening and Assessment of Coronary Heart Disease in HIV-Infected Patients (July 8, 2008)
From Circulation
- Insulin Resistance May Predict Risk of Cardiovascular Disease in HIV (May 8, 2008)
From aidsmap.com
- Conventional Cardiovascular Risk Factors in HIV Infection: How Conventional Are They? (May 2008)
In Current Opinion in HIV and AIDS
- Heart Attack Rates Not Rising Among HIV-Positive People, Study Finds (April 23, 2008)
From Medscape
- Protease Inhibitors Increase Fibrinogen Levels: Increased Risk for Hardening of the Arteries (April 8, 2008)
In aidsmap.com
- Anti-Inflammatory Drug Could Reduce Heart Disease Risk in Patients With HIV (March 14, 2008)
From aidsmap.com
- Abacavir, Didanosine Associated With Higher Heart Attack Risk, D:A:D Study Finds (February 5, 2008)
An interview with Jens Lundgren, M.D.
In 15th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Increased Risk of Myocardial Infarction Associated With Abacavir and ddI (February 4, 2008)
From HIV i-Base
- Position Statement by the D:A:D Steering Committee (February 4, 2008)
A discussion of the significance of a study examining the association between use of abacavir, didanosine and lamivudine and the risk of myocardial infarction.
To read PDF, click here
From D:A:D Steering Committee
- Short-Term Ritonavir Exposure Impacts HDL, CD36 and Triglyceride Levels in Healthy Volunteers (February 4, 2008)
Marta Boffito, M.D., Ph.D., discusses her study, which examines the possible role of ritonavir in increasing cardiovascular risk.
From The Body PRO
- Study Finds Heart Trouble With Ziagen and Videx (February 4, 2008)
From Project Inform
- HIV-Positive Patients Have High Prevalence of Asymptomatic Heart Disease in US Study, But Traditional Risk Factors and Cocaine Use Main Causes (January 23, 2008)
From aidsmap.com
- Spanish Find Low Prevalence of Peripheral Arterial Disease in HIV-Positive Patients With Heart Disease Risks (January 9, 2008)
From aidsmap.com
- Ten-year Predicted Coronary Heart Disease Risk in HIV-Infected Men and Women (October 15, 2007)
In Clinical Infectious Diseases
- Anti-HIV Treatment, Weight and Low Income Risk Factors for Heart Disease (October 1, 2007)
From aidsmap.com
- Hardening of the Arteries Found in One in Five Patients in Swiss HIV Cohort (September 17, 2007)
From aidsmap.com
- IAS: Cardiovascular Disease and Diabetes Increasing as Causes of Death for People With HIV in Brazil (July 25, 2007)
From aidsmap.com
- Insight Into the Burden of Coronary Artery Disease in HIV-Infected Patients (July 24, 2007)
This is the first moderately sized study to examine at a histological level the lesions associated with the increased risk of myocardial infarction among HIV-infected individuals that has been reported in multiple case series and cohort studies. Margaret Hoffman-Terry, M.D., reports.
In 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, from The Body PRO
- Cardiovascular Risk Assessment, Treatment Vital for HIV Patients on Therapy (June 20, 2007)
From American Heart Association
- High LDL Cholesterol Levels May Drop by Switching Sustiva to Viramune, Study Says (June 12, 2007)
From AIDSMeds.com
- Antiretroviral Therapy Carries Same Risk of Ischaemic Heart Disease as 1-4 Cigarettes a Day, Danish Study Shows (May 23, 2007)
From aidsmap.com
- Heart Attack Risk Seen in Drug for Diabetes (May 22, 2007)
In The New York Times
- Popular Diabetes Drug May Increase Heart Attack Risk, FDA Warns (May 22, 2007)
The widely used diabetes drug Avandia (rosiglitazone) may increase a person's risk for heart proboems, according to a new warning issued by the U.S. Food and Drug Administration (FDA).
In The New York Times
- No Imminent Epidemic of Heart Disease Among HIVers on Meds, Expert Says (May 1, 2007)
From aidsmap.com
- HIV Infection Doubles Risk of Heart Attack in US Patients; Risk Trebled in Women (April 27, 2007)
From aidsmap.com
- HIVers -- Particularly Women -- More Likely to Have Heart Attacks, New Study Finds (April 24, 2007)
In Washington Post
- Metabolic Complications: A CROI Round-Up (February 28, 2007)
Includes an analysis of research examining lopinavir/ritonavir vs. efavirenz, the use of growth hormone releasing factor to treat fat gain, the link between cardiovascular disease and HIV treatment, the use of ezetimibe (a choleserol-reducing agent) and the latest on bone health in HIV-infected patients.
In Exclusive Coverage of the 14th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
- Is HIV Causing Cardiovascular Disease by its Own Effects on Cholesterol? (December 18, 2006)
From aidsmap.com
- Deep Vein Thrombosis Risk Increases as HIV Disease Worsens (August 7, 2006)
In aidsmap.com
- Will HIV Meds Raise Your Cholesterol? Depends on Your Race, Study Suggests (March 2006)
In PLoS Medicine
- Cardiovascular Risk and Antiretroviral Therapy: New Research on Epidemiology, Pathogenesis and Treatment (February 8, 2006)
In The 13th Conference on Retroviruses and Opportunistic Infections
- HIV JournalView: A Supersized Epidemic: The Twin Problems of Obesity and HIV (January 2006)
Part of David Wohl, M.D.'s review of the top 10 HIV research reports of 2005.
In HIV JournalView, from The Body PRO
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