When to Start HIV/AIDS Treatment: Research

Show Archived (Historical) Articles

Study Suggests Immune Systems of Untreated HIV-Infected Individuals May Deteriorate Faster Than Previously Thought (July 29, 2009)
From U.S. National Institute of Allergy and Infectious Diseases
Delays in Starting Treatment Common in ART Programs (July 23, 2009)
Late initiation of antiretroviral treatment following diagnosis is contributing to the continuing high death rate among people who present with low CD4+ cell counts in eight sub-Saharan African countries.
From aidsmap.com
Treating HIV Earlier Could Save 76,000 Lives in South Africa (July 23, 2009)
A new study finds that initiating antiretroviral therapy when a patient's CD4+ cell count drops below 350 cells/mm³ could save 76,000 lives in South Africa alone over the next five years.
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
IAS Welcomes Trial Findings Showing Benefits of Earlier Antiretroviral Treatment (June 19, 2009)
From International AIDS Society
Questions and Answers: The CIPRA HT 001 Clinical Trial (June 8, 2009)
From U.S. National Institute of Allergy and Infectious Diseases
Starting Antiretroviral Therapy Earlier Yields Better Clinical Outcomes (June 8, 2009)
Interim review leads to early end of clinical trial in Haiti.
From U.S. National Institute of Allergy and Infectious Diseases
Study Shows Decreased Risk of Death From Opportunistic Infections With Earlier Antiretroviral Treatment (May 19, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Early Initiation of Antiretroviral Therapy Improves HIV Survival Rates, Study Says (April 30, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Effect of Early Versus Deferred Antiretroviral Therapy for HIV on Survival (April 30, 2009)
In The New England Journal of Medicine
Should the CD4 Threshold for Starting ART Be Raised? (April 18, 2009)
In The Lancet
Timing of Initiation of Antiretroviral Therapy in AIDS-Free HIV-1-Infected Patients: a Collaborative Analysis of 18 HIV Cohort Studies (April 18, 2009)
In The Lancet
Study Supporting Earlier Antiretroviral Treatment "Not Definitive," NEJM Editorial Says (April 10, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Delaying HAART Might Prevent Complete Immune System Recuperation, Study Says (April 9, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Effect of Early Versus Deferred Antiretroviral Therapy for HIV on Survival (April 9, 2009)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
Study Supports Earlier Antiretroviral Treatment, Researchers Call for Amended Recommendations (April 9, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
When to Start Treatment: Leave it No Later Than 350, Major Studies Agree (April 9, 2009)
From aidsmap.com
Earlier Antiretroviral Treatment Could Reduce Risk of Death in HIV-Positive People, Study Finds (April 2, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
More Evidence Favors Early Treatment (Winter/Spring 2009)
In Bulletin of Experimental Treatments for AIDS, from San Francisco AIDS Foundation
Treating AIDS Infection Immediately Might Stall Immune Decay (February 17, 2009)
In CDC HIV/Hepatitis/STD/TB Prevention News Update, from U.S. Centers for Disease Control and Prevention
Starting HAART Earlier Might Reduce Mortality Rates, Study Says (February 12, 2009)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Ever Upward: "When to Start" Debate Turns to CD4+ Cell Count of 500 (February 9, 2009)
Dueling studies -- one presented by Mari Kitahata, M.D., the other by Jonathan Sterne, M.D. -- offer strikingly different views on the benefits of HAART initiation at a CD4+ threshold of 500. However, both appear to solidify the wisdom of starting therapy before CD4+ cell count drops below 350.
In The 16th Conference on Retroviruses and Opportunistic Infections, from The Body PRO
Starting Therapy Earlier Found to Improve Survival (January/February 2009)
Study raises the implications of more testing, less transmission.
To read PDF, click here
In Positively Aware, from Test Positive Aware Network
Starting Treatment at CD4 Above 350 May Bring Extra Immune Benefits, Study Says (January 13, 2009)
From aidsmap.com
Earlier Treatment of HIV Could Help HIV-Positive People Avoid Long-Term Complications, Recommendations Say (August 5, 2008)
A panel of the International AIDS Society-USA has issued new recommendations for when physicians should initiate HAART.
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
HIV Meds May Help Prevent Illness and Death at CD4 Counts Above 350, Study Finds (April 14, 2008)
In aidsmap.com
Starting HIV Meds Early Is Better for Your Health Than Waiting, Study Says (April 14, 2008)
In aidsmap.com
CROI: Could earlier ART Reduce Risk of Death from Non-AIDS Related Illnesses in People With HIV? (February 6, 2008)
From aidsmap.com
New HIV Treatment Guidelines in Europe Recommend Starting Meds at 350 (October 25, 2007)
In aidsmap.com
Possible Benefit to Starting Treatment at High CD4 Count, Massive Study Finds (August 24, 2007)
The study of more than 17,000 people who had never taken HIV meds found that, even among those with a CD4 count well over 350, the higher the count, the less likely they were to develop an AIDS-related illness or die.
From aidsmap.com
First-Line Therapy: What Should You Take? (July 2, 2007)
Discusses Choosing Among Drug Classes , Efavirenz-Based Combinations , Ritonavir-Boosted PI-Based Regimens and Considering NRTIs.
From The Body PRO
Three Months of Meds in Early Infection May Slow Down HIV in the Long Run (June 26, 2007)
From aidsmap.com
Voices Grow Louder in Support of Earlier HAART Initiation (January 12, 2007)
From aidsmap.com
Large Study Backs Starting HIV Treatment When CD4 Count Is Above 350 (January 9, 2007)
From aidsmap.com
Veterans Medical Affairs Researchers to Request NIH Funding for Study Examining Best Time to Start Antiretroviral Treatment (January 8, 2007)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
CD4 Percentage May Be Useful for Deciding Whether to Start HIV Treatment (January 5, 2007)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Strategic Use of Antiretroviral Therapy: What to Use and When? (September 28, 2006)
In 46th Interscience Conference on Antimicrobial Agents and Chemotherapy
Two Studies Examine Potential Benefit of Beginning ART During Acute Infection (September 1, 2006)
In Kaiser Daily HIV/AIDS Report, from Henry J. Kaiser Family Foundation
Optimal Timing of HAART Initiation Does Not Differ With Regimens That Include Efavirenz or Ritonavir-Boosted Protease Inhibitors (August 15, 2006)
In XVI International AIDS Conference
Gilead Warns Against Use of Triple-NRTI Regimen 3TC, ddI, Tenofovir (October 14, 2003)
To read PDF, click here
From U.S. Food and Drug Administration
Early Virologic Non-Response in Patients With HIV Infection Treated With Lamivudine, Abacavir and Tenofovir (July 25, 2003)
"Dear Healthcare Provider" letter from GlaxoSmithKline.
From U.S. Food and Drug Administration

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