Zidovudine Dosage

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An Overview of Retrovir (Zidovudine, AZT)

zye-DOE-vyoo-deen Brand Name: Retrovir Other Name(s): AZT, Azidothymidine, ZDV Drug Class: Nucleoside Reverse Transcriptase Inhibitors What is zidovudine? Zidovudine is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). It works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal reverse transcription, HIV's reverse transcriptase enzyme (a type...

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infant zidovudine: recommendations for dose escalation with weight gain?

I know standard dosage for zidovudine for an infant born to an HIV positive mother is "2 mg/kg body weight q6h" as part of the MTCT prevention. In 6 weeks time however, an infant easily weighs a kilo, to 1.5 kg more which is up to 50% of...

Response from Katherine Luzuriaga, M.D.

University of Massachusetts, Medical School

In our clinic, we usually see babies at 1 and 4 weeks to see how things are going, check their weights, and to draw bloods to check for infection. If weight is increased by more than 10% of the baby's previous weight, we adjust the dose. If... Read more »

Underdosage of Zidovudine

Dear SirI am writing for the 2nd time. My son aged 5 years has been recently diagnosed as HIV+ His CD4 is 384. His doctor started him on Zidovudine 6ml twice a day, Lamivir 6.5 ml twice a day, and Nevirapine (initially 6 ml once a day). His weight...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.This reply comes from our good friend and colleague, Andy Pavia, MD from University of Utah:I don't think there is any risk at all from 2 weeks of underdosing of zidovudine. First of all, zidovudine resistance develops... Read more »

developed lipoatrophy while on videx,zidovudine and aluvia

what is lipoatrophy(from 2006 on videx and zidovudine) and can it be treated and how but i'm now switched to truvada and aluvia after alerting my doctor about my fat distribution last month ...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Fat loss (lipoatrophy) and fat gain have been linked to zidovudine and somewhat less so to didanosine (Videx). Switching to Truvada and Aluvia (lopinavir/ritonavir) may stabilize the fat loss with slow recovery. Its impact on areas of fat gain is... Read more »

zidovudine

under which of the following conditions is azt (zidovudine) prescribed for patients suffering from hiv?...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Zidovudine (AZT, Retrovir) is used as part of combination therapy for the treatment of HIV-infected individuals or in special circumstances for the prevention of HIV infection, following high-risk exposure. BY... Read more »

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Liver Function

Posted by NYRN, 1 Reply

I'm taking viread, invirase, didanosine, zidovudine and valtrex and my latest labs indicate high on the liver screens. Has anyone had any liver issues - I don't drink so it's not that! Read more »

high lipids

Posted by Anonymous

Has anyone tried this product http://www.policosanol.com/monograph.htm#dosage
if so please post results/side effects
Thanks

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NAC

Posted by Anonymous, 2 Replies

Poz 16 years. Should i be taking NAC? Any stories, suggestions? good /Bad? What form and dosage? Thanks! Read more »

unprotected sex----ECLIA test

Posted by haohaode, 1 Reply

on 4 February, i had unprotected vaginal sex with a thai sex worker for less than two minutes.
within 24 hours i took Kaletra, lamivudine and zidovudine for 28 days.
on 30 March(8 weeks later), this woman had ECLIA/ Roche Diagnostics test with... Read more »

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