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Zidovudine Bone Marrow Suppression

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Ask the Experts

Side effects of Combivir and Kaletra

A patient on a combination of Combivir and Kaletra develops elevated liver enzymes with some bone marrow suppression.What other combination should be used in order to stop the side effects of the drugs?
Eric Daar, M.D.

Response from Eric Daar, M.D.

UCLA School of Medicine
...to reinitiation of an alternative regimen.That being said, certainly the AZT (zidovudine) in combivir can be associated with bone marrow suppression, particularly a decrease in the red and white blood cells. In addition, both AZT and Kaletra can... Read more »

AZT (Zidovudine 300mg)

I just started taking AZT. I have always bruised very easy (since I was a child). Is there any... Read more »

Add a single med to my existing combo?

Dear Docs,Thank you so much for the invaluable support and information. My question: HIV positive... Read more »
Articles
Test Positive Aware Network

Retrovir

...nausea, and fingernail discoloration. Zidovudine (AZT) has been associated with alteration of various cells in the blood through bone marrow suppression, resulting in anemia (low red blood cell counts) and/or neutropenia (low white blood cell... Read more »
Test Positive Aware Network

Zerit

...(pentamidine), and Videx (ddI) may increase the risk of pancreatitis. Should be used with caution by people with pre-existing bone marrow suppression, kidney problems, or peripheral neuropathy. Retrovir (zidovudine, AZT) and Zerit should not be... Read more »
AIDS InfoNet

Zidovudine (Retrovir, AZT)

... What Is Zidovudine? Who Should Take Zidovudine? What About Drug Resistance? How Is Zidovudine Taken? What Are the Side Effects? How Does Read more »
AIDS InfoNet

Combivir (Zidovudine + Lamivudine)

...Other Drugs? What Is Combivir? Combivir is a pill that contains two drugs used as part of antiretroviral therapy (ART): zidovudine (Retrovir, AZT) and lamivudine (Epivir, 3TC). Combivir is manufactured by ViiV Healthcare. Generic versions... Read more »
Connect With Others

Infectious or Intoxication Diseases?

Posted by Anonymous
...distinctly declining since 1990/91, the time when therapists noticed that AZT in 1500 mg doses were not tolerable for their patients (bone marrow suppression). At that time, however, we had already treated a whole generation of AIDS patients into... Read more »

Suppressed immune system

Posted by Anonymous, 2 Replies
Hello, I was just wondering what types of things suppress your immune system, which I know can delay your HIV test from coming up positive? Read more »

i am living with hiv and have been fairly healthy.

Posted by Anonymous, 1 Reply
...sick, I should keep pushing myself. I hear of a new therapy and then later read about the Stephen Johnson's side effect or the bone marrow suppression or the possible nauseau and headaches -- and know with my history if there is a side effect... Read more »

How can I suppress my libido?

Posted by Anonymous
I make stupid irresponsible choices that puts me at risk. Is there medication I can take (or anything I can do) to suppress my libido so that I'm not so tempted to do things that can get me into trouble? Read more »