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Ziagen Medication

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Brand name: Ziagen Generic name: abacavir sulfate (abacavir), or ABC Class: Nucleotide reverse transcriptase inhibitor(nucleotide, NtRTI, or nuke) Manufacturer: ViiV Healthcare, , (877) 844-8872 AWP: $670.37/month, $161.78 for 240 mL solution (20 mg/mL) Standard Dose: Two 300 mg tablets once a day (or one 300 mg tablet twice a day), with or without food, with no dietary restrictions; scored tablets...
Ask the Experts

Avoid Ziagen if VL > 100,000

Dear Doctor(s):Thank you for the service, information and assistance you are providing here.In "25 Things You Should Know if You Are HIV-Positive" in this website (, point #8 says, "If your...
Gerald Pierone, M.D.

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast
This simply means that you would not use a triple nucleoside regimen (like Trizivir alone) for high viral load. It would not be a problem to use Ziagen as one of the medications, just not the anchor. For example, Ziagen, Epivir, and Sustiva would be... Read more »

Temparature for Ziagen

My partner is concerned about the temperature warning of ZIAGEN. It says medication must be kept between 67 and 76 degrees, a pretty narrow range. Yesterday, temperature in house was about 62 degrees; and in summer, even with air conditioning, it...
Edwin DeJesus, M.D., F.A.C.P.

Response from Edwin DeJesus, M.D., F.A.C.P.

The storage recommendations in most medications are based on how these medications were studied during their development. The temperature range is usually tighter than what it probably has to be, especially for short term storage (30 days, or... Read more »


Dear Drl Holodniy:I have recently had a genotype worked and found that I am resistant to all HAART medications currently approved by the FDA. The only meds that they did not test for were Ziagen and Agenerase, the newly approved treatments for...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
The key info you need (and me to make the call)is what mutations were present on the genotype. I can answer both of your questions together. Key mutations to AZT and 3TC, will make the virus resistant to Ziagen. In fact the more AZT mutations you... Read more »

Adding Ziagen

Doctor after about 5 years on crixivan/combivir I was switched to viramue/combivir for about 8 months. I never had a detectable VL until today when I went to the doctor for a routine follow up. VL 275 Ts 852, 30 . The doctor added ziagen and he had...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.The addition of abacavir (Ziagen) to a three-drug regimen when one has a low viral load, like you do is called an intensification strategy. This approach is different than when you have a higher viral load (say in the mid-... Read more »
Connect With Others

swithching Ziagen to Viread...fatigue

Posted by Anonymous, 2 Replies
Im 5 yrs in Ive been taking epivir,ziagen and viramune.
Fatigue bacame an increasingly intolerable issue when I be gan Ziagen.(sorry, at yr. 3 I replaced d4tZerit with Ziagen.My legs were melting away)
Anyway going to try replacing the Ziagen with... Read more »


Posted by Anonymous, 2 Replies
I know this is the wrong forum, but the treatment forum isen't that active. I was told that they have developed a test for sensitivity to ziagen(for rechallenge purposes)and I can't find anything...Has anyone heard of this??

Read more »

new drug...ziagen

Posted by Anonymous, 1 Reply

Just watched the news and the FDA has just approved a new drug
(Ziagen). They say the Ziagen is one pill taken twice a day and is
usually taken with AZT. What a tremendous relief... Read more »


Posted by Anonymous, 4 Replies
My doc just started me on Abacavir, to replace the Preveon I was taking, in combination
with AZT and Viramune. I don't know much about Abacavir, except what I have found
on Project Inform's site. I would like to hear... Read more »