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Why Is Atripla Taken Without Protease Inhibitor

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

Resistance to protease inhibitors

If you have were infected years ago, before protease inhibitors came out, and you have not yet been on them, is it possible that because of loads of other treatments you are also resistent to them?And, if you have only taken Crixivan with treatment...
Susan Little, M.D.

Response from Susan Little, M.D.

University of California San Diego
No-if you have not taken a protease inhibitor and were infected before they became widespread in the community, then it would be extremely unlikely for you to be resistant (nearly impossible, really), despite possibly being resistant to many other... Read more »

new protease inhibitor

I am on a isentress, selzentry and reyataz, norvir regimen and my hepatitis dr wants to me to start the new protease inhibitor for hepatitis. will any of my HIV drugs will interfere with the new Hepatitis medication?Thank you very much...
Barbara McGovern, M.D.

Response from Barbara McGovern, M.D.

Tufts University School of Medicine
You ask an excellent question. Telaprevir is under study right now in combination with pegylated interferon and ribavirin among HIV/HCV coinfected patients. The preliminary results show that the majority of patients are achieving viral suppression... Read more »

Injectable Protease Inhibitors

Given the gastronitestinal side effects that make protease inhibitors so unpleasant shouldn't there by an injectable option/formulation to bypass the stomach? Fuzeon has problems too, but many people do well for years injecting that or insulin....
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Your point is well taken though there are costs and side effects associated with the subcutaneous injection route as well. We have had some patients in whom we have put in a percutanous feeding tube from the skin to the stomach or small bowel to... Read more »

Protease Inhibitors

Why are PI's used sometimes in first line therapy ?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.Every patient brings individual sets of needs and concerns to the clinic. We always try to have a discussion about the risks and benefits of current DHHS and IAS-USA recommended treatments. There are a number of reasons why... Read more »
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lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »