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Who Uses Protease Inhibitors

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AIDS InfoNet

Protease Inhibitors in Development

These drugs have not been approved by the Food and Drug Administration (FDA) for use against HIV. Protease Inhibitors These drugs block the protease enzyme. When new viral particles break off from an infected cell, protease cuts long protein strands into the parts needed to assemble a mature virus. When protease is blocked, the new viral particles cannot mature. Protease Inhibitors in Development Several firms are trying to develop a new...
Ask the Experts

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS.... Read more »

Viability of Protease Inhibitors

How are Protease Inhibitors useful in treating HIV? It seems that they would need to be in the blood before infection, or immediately upon infection to be able to work, otherwise the genetic information would already be inside the cell. What is...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
Studies are ongoing to look at post exposure prophylaxis (PEP) with protease inhibitors after high risk exposures. San Francisco General Hospital AIDS Program is taking the lead on this. Look back studies with AZT alone given within 4 hours of a... Read more »

protease inhibitors and children

Have protease inhibitors been approved for children with HIV yet? Are they aseffective in children as in adults? I knowsome kids who were part of a trial study on protease inhibitors and had goodresults.. but I know other kids who are in fosterhomes...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
The protease inhibitors are not yet approved for children, but they arewidely used. Ritonavir is available in a liquid formulation that I'm toldtastes pretty nasty. Nelfinavir will be available in a powder form that I'mtold will taste ok... Read more »

Going off Protease Inhibitors

I am in a situation, like many, where the protease inhibitors are not really working for me very well any more. My T cells are at 300 and my viral load is at 29,000. I am a long term survivor (ten years) who was diagnosed with AIDS as a result of...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your question.It certainly sounds like you have evidence of viral resistance to your current treatments. An important decision at this point is whether to continue on therapy (with a treatment switch) or to discontinue therapy.I probably... Read more »
Connect With Others

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies
I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply
Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous
I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol
Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »