Who Takes Integrase Inhibitors

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An Overview of Isentress (Raltegravir, MK-0518)

ral-TEG-ra-vir Brand Name: Isentress Other Name(s): MK-0518, MK0158, RAL Drug Class: Integrase Inhibitors ISENTRESS ® ( eye sen tris ) ( raltegravir) Tablets Read the patient information that comes with ISENTRESS before you start taking it and each time you get a refill. There may be new information. What is ISENTRESS? ISENTRESS is an anti-HIV (antiretroviral) medicine used for the treatment of HIV. The term HIV...

Ask the Experts

Merck integrase inhibitor

Dear Doctor,You wrote a couple of days ago that the Merck integrase inhibitor will be available shortly. As a treatment experienced hiver (+ since 1990) I would like to know what this med will offer in comparison to the already available...

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

This will be a medication that works completely differently than any of the currently available HIV meds. Therefore, for someone like yourself who has had HIV for a while and may have virus that has accumulated HIV drug resistance, the integrase... Read more »

ls isentress integrase inhibitors the future for hiv meds ???

Hi Dr Henry,l have been taking different hiv meds for the past 8 years, and its not much fun with the side effects of the meds, l am reading about isentress integtase inhibitors and would like to know your opinion, is this the new step in hiv...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Raltegravir is a promising new HIV treatment known as an integrase inhibitor. It has mostly been used in patients with resistant virus in complex regimens where it has performed well. It has to be taken twice a day. So far it appears well tolerated... Read more »

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work. Protease, reverse transcriptase and integrase. Why havent we created an integrase inhibitor. And where are we as far fusion inhibitors. Or any type of...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,Where are they? Well, at present, they are "in the pipeline." Exactly how quickly these and other agents will move through the pipeline into broader-based clinical trials, then on to compassionate use/expanded access programs, then... Read more »

New Integrase inhibitor and lipodystrophy risk

There is a once a day integrase inhibitor with a non-PI booster coming up soon, isn't there? What is the integrase inhibitor called and what class does the booster belong to? Setting aside the relative newness of these drugs (and therefore the...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

Hello and thanks for posting. The new integrase inhibitor medication is called elvitegravir and the booster is GS 9350. The booster is one of a new class of drugs designed specifically to inhibit the CYP3A liver enzyme system. We already know that... Read more »

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Integrase Inhibitor

Posted by Survivor

I just wanted people realize there is hope and continued very active DRUG DISCOVERY!

Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs

Whitehouse Station, N.J.-based Merck and Foster... Read more »

Today's LA Times Article - Integrase Inhibitors

Posted by Anonymous

Very hopeful! (Despite the sad title.)

http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more »

Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous

I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies

I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

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