Who Takes Fusion Inhibitors

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Fusion and Attachment Inhibitors

Note: Several fact sheets describe drugs that are being tested against HIV: Fact Sheet 410 : nucleoside analog reverse transcriptase inhibitors (nukes) Fact Sheet 430 : non-nucleoside analog reverse transcriptase inhibitors (NNRTIs or non-nukes) Fact Sheet 440 : protease inhibitors Fact Sheet 470 : other antiretroviral drugs in development Fact Sheet 480 : immune therapies These drugs have not been approved by the Food and Drug...

Ask the Experts

Fusion Inhibitors

Can you shed any light on what, if any, of the preliminary reports on fusion inhibitors may include as far as side effects? I guess I am assuming they have done some human trials??...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

T-20 = Fuzeon is the only fusion inhibitor soon to be more widely available. Since it acts outside of cells (blocking fusion) its toxicity would be expected to be low and that has been the case in major clinical trials conducted to date. The major... Read more »

Fusion inhibitors and clinical trials.

I have recently reached the point where I need to start taking anti-HIV medications and I am seeking your advice on how to proceed.Our local AIDS Clinical Trials Unit needs people who are treatment-naive for a study involving fusion inhibitors in...

Response from Gerald Pierone, M.D.

AIDS Research and Treatment Center of the Treasure Coast

I think that your primary ID doctor is correct. A simple regimen would probably work as well with fewer side effects. Fusion inhibitors require daily injections and are no walk in the park. If you do decide to participate in this trial you should... Read more »

Fusion Inhibitor and Cosmetic Surgary

If i am taking T20 and added regimen would their be a problem if they perform a Tummy Tuck on me well the reason i ask you is because you inject at the skin level tissue level and tummy tucks are in the tissue area and well i take it in my sholder...

Response from Carol Salisbury, APRN-BC, MSN

Michigan State University College of Nursing

Hi,T-20 also called Fuzeon is injected in the fatty tissue (subcutaneous or "sub-q") in your abdomen and also in your thighs, back of arms and can be injected in the flank or "love handles". A tummy tuck should not deter from... Read more »

fusion inhibitors

Is there a pill form of any fusion inhibitors coming soon?...

Response from Don Kurtyka, ARNP

University of South Florida School of Medicine

Fuzeon is the only fusion inhibitor currently approved by the FDA. Fusion inhibitors are part of a bigger classification of drugs called entry inhibitors which also includes attachment inhibitors, CXCR4 inhibitors and CCR5 inhibitors. There are... Read more »

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Connect With Others

Fusion Inhibitor News?

Posted by Anonymous

Does anyone know if the fusion inhibitor trials (phase III) are going OK, or where to go for an update? Last I heard 700 patients in 100 countries were in the study for T-20(?)
I went to the Trimeris site and didn't see anything new.

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Hyperglycemia as a result of Protease Inhibitors

Posted by Anonymous

I found a product for reducing glucose levels. It is called Meishan Tea. They make 4 different kinds of tea and I have people that are showing tremendous results on all 4 kinds. However, the people that are presently taking the tea do not have AIDS.... Read more »

lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies

I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

Entry Inhibitors

Posted by Anonymous, 1 Reply

Does anyone know anything about the new entry inhibitors? I think Pfizer and Schering both have drugs in development. Should we be hopeful? Read more »

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