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Who Takes Saquinavir

Here's a taste of what has to offer on this topic:
Get the Facts
AIDS InfoNet

Saquinavir (Invirase)

... What Is Saquinavir? Who Should Take It? What About Drug Resistance? How Is It Taken? What Are the Side Effects? How Does It React With Other Drugs? What Is Saquinavir? Saquinavir, also called Invirase, is a drug used as part of
Ask the Experts

Saquinavir & grapefruit juice

My Dr. suggested that I may substitute grapefruit juice for the fatty mealnormally taken withSaquinavir. Mind you, he recommended the fatty meal, but said, when a fattymeal is not possible,drink grapefruit juice! I have asked my pharmacists about...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...Unfortunately, given the poor bioavailability of saquinavir you need to doeverything you can to increase blood levels. In my mind that means doingboth -- taking it with a fatty meal AND Read more »

Ritonavir/Saquinavir Combination -v- Crixivan

I am currently taking AZT, Nevirapine (Viramune), 3TC and Crixivan. I have been following the debate about whether toincrease Crixivan dosage from 800mg to 1000mg because of the effects of Nevirapine, and have chosen to do this.However, I found the...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...I think that ritonavir/saquinavir is at least as effective as indinavir (Crixivan). Changing from one protease inhibitor to another is not a problem provided you Read more »

High Dose Saquinavir

Dear Dr. Gallant, Currently on azt,3tc, and 7200mgs/day saq. Thinking ofswitching to Crix. If Saq is still working wouldyou suggest this or not? Also what is your opinion of high dose saq? Iffailure occurs do you recomend changing one or alldrugs in...
Joel Gallant, M.D.

Response from Joel Gallant, M.D.

Johns Hopkins University, School of Medicine
...regimen, there'd be nothingwrong with sticking with it, unless the change involved adding ritonavir ornelfinavir, which increase saquinavir levels.If your viral load is detectable, then it's probably better to change morethan one drug rather than... Read more »

Saquinavir/Ritonavir/D4T absorption

Dear Dr, Your website has been a great source of information and support forme. Thank you for aswering all thosequestions. Maybe you have been answering this question previously.... I knowthat this combo is best be taken with a fattymeal. Because in...
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
Frank, Read more »

An Overview of Invirase (Saquinavir mesylate)

... sack-KWIN-uh-vihr MEH-sih-LATE --> Brand Name: Invirase Other Name(s): Ro 31-8959/003 (Saquinavir mesylate), SQV, Saquinavir mesylate, Saquinavir monomethanesulfonate (Saquinavir mesylate) Drug Class: Protease Inhibitors Read more »
U.S. Food and Drug Administration

Ongoing Safety Review of Invirase (Saquinavir) and Possible Association With Abnormal Heart Rhythms

...Administration (FDA) is reviewing clinical trial data about a potentially serious effect on the heart from the use of Invirase (saquinavir) in combination with Norvir (ritonavir). The data suggest that together the two drugs may affect the... Read more »
U.S. Food and Drug Administration

Invirase (Saquinavir) Labels Now Contain Updated Risk Information on Abnormal Heart Rhythms

...Administration is notifying the public that new risk information has been added to the label of the antiviral drug Invirase (saquinavir), describing a potential change in the electrical activity of the heart when Invirase is used with another... Read more »

Saquinavir (Fortovase, Invirase)

... --> Brand Name: Invirase Clase de medicamento: Inhibidor de la proteasa El mesilato de saquinavir, conocido tambiĆ©n como Invirase, y el saquinavir, comercializado antes en los Estados Unidos como Fortovase, pertenecen a la Read more »
Connect With Others

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies
I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting. I have just spoken to my son again. He was finally able to convince... Read more »

What should I think?

Posted by motherinlaw, 9 Replies
I will try not to make this too son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother. My son and daughter-in-law seem not to... Read more »

Resisting Resistance - A Story

Posted by Survivor, 1 Reply
...placebo for the first part of the trial. I regained my weight and enrolled in a study of the first protease inhibitor, Invirase (saquinavir). The background drugs in this study were AZT and ddC -- two drugs I had already used. So with Invirase as... Read more »

Med resistance on Norvir/Saquinivar..anyone else?

Posted by Anonymous, 1 Reply
...I have been on Norvir/Saquinavir for 7 years. Starting to show resistance. Panicking a little, they worked for so long, controlled side effects. Doctor wants Read more »