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Who Is At Risk For Mitochondrial Toxicity

Here's a taste of what has to offer on this topic:
Ask the Experts

Reducing Dose Of Truvada?

I am wondering if it's virologically safe to reduce my Truvada dosage to half a tablet daily OR one full tablet every other day to minimize the risk of developing the NRTI associated side effects (mitochondrial toxicity & Kidney/ bone injury) ?I am...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
...The risk for mitochondrial toxicity is low with Truvada. Truvada has been a highly effective NRTI backbone for HIV treatment partly because of its favorable pharmacokinetic Read more »

switching combivir for truvada

I was diagnosed in April 2003 and have been on Sustiva/Combivir ever since - good labs, good... Read more »

Growing concern around mitochondrial toxicity

I have been on truvada and sustiva for 9 months and for the past few weeks have been experiencing... Read more »
Project Inform

Mitochondrial Toxicity and Lactic Acidosis Fact Sheet

...Contents Introduction What Are Mitochondria? How Anti-HIV Drugs Affect Mitochondria What Are the Common Results of Mitochondrial Toxicity? Mitochondrial Toxicity and Lactic Acidosis What Is Fatty Liver? Mitochondrial... Read more »
AIDS InfoNet

Mitochondrial Toxicity

...high levels of lactic acid that can be caused by all of the nukes. Unfortunately, there is very little research on how much mitochondrial damage each ARV causes to different parts of the body. We also don't know which combinations of drugs cause... Read more »
The Body PRO

Cutting-Edge Issues in HIV Medicine (Symposium)

...everything is good news: there is an increased risk of hepatotoxicity in co-infected patients, as well as an increased risk of mitochondrial toxicity associated with NRTI, especially in patients on ribavirin. Dr. Dove then reviewed the current... Read more »
The Body PRO

Incidence of Symptomatic Hyperlactatemia With FTC

...St. Louis (and sponsored by Gilead Sciences, the maker of FTC) to determine if FTC was associated with the development of SH. Mitochondrial toxicity has been shown to be associated with the development of SH. Studies previously performed have... Read more »
Connect With Others

Am I Infected

Posted by delhiguy, 3 Replies
I am 30 YO guy. Worried that I may have got infected. I met this friend of mine on 5th of Dec 2010 which was just a causual meeting after 5 years. After having drinks she started touching me and I got aroused and we end up mating. While in act, she... Read more »

I'm major stressed is this low risk/no risk?

Posted by xandernumpty
...boxers and then went and cleaned up. I was sober.. well one beer. But he was a complete random stranger. Have i put myself at risk?, i called an sti hotline they said no risk, the health clinic nurse said minimal whilst the health counsellor... Read more »

Sanitary Pads - Real risk or no risk?

Posted by Anonymous, 1 Reply
...was already healing). My question is: if the pad was soiled with blood and came into contact with the abrasion, would I be at risk for HIV? Are there any documented cases on this? Please help me. Thanks. Read more »

Low Risk or No Risk?

Posted by SamGlue, 2 Replies
...what happened. So I rang the needle hotline and was told different information. They assured me that there was actually NO risk at all because the needles given out to drug users in Australia are small guage needles but moreso becuase any blood... Read more »