When Will A Protease Inhibitor For Hiv Come Out For Treatment

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Articles

New Label Information Affecting All Approved Protease Inhibitors for Treatment of HIV

The approved protease inhibitors for the treatment of HIV-1 infection now all include the following drug-drug interaction information: Revatio (sildenafil) as a contraindicated medication when prescribed for the treatment of pulmonary arterial... Read more »

Important Drug Warning: Results of Pharmacokinetic Study in Healthy Volunteers Given Victrelis (Boceprevir) and Ritonavir-Boosted HIV Protease Inhibitors May Indicate Clinically Significant Drug Interactions for Patients Coinfected With Chronic Hepatitis C and HIV

Dear Health Care Professional, The purpose of this communication is to inform you of recent pharmacokinetic study results evaluating drug interactions between VICTRELIS, an oral chronic hepatitis C virus (HCV) NS3/4A protease inhibitor, and... Read more »

Long-Term Protease Inhibitor Treatment Increases Men's Risk for Heart Attack, Study Says

Long-term antiretroviral drug treatment including protease inhibitors increases HIV-positive men's risk for heart attack, according to a study published in the Nov. 21 issue of the journal AIDS , Reuters Health reports. Dr. Murielle... Read more »

Ask the Experts

New Treatment? -- OK to Stop Protease Inhibitor

My Doctor told me to permanently stop my protease inhibitor, I have been on Viracept 1250MG, Zerit 40MB, and Epivir 150MG, all twice daily for 3 years. My CD4 is 1056 and my viral load is undetectable, less than 50. My doctor wants me to take DDI...

Response from Kathleen E. Squires, M.D.

University of Southern California's Keck School of Medicine

Your physician clearly knows the specifics of the course of your HIV infection; it is difficult to try and second-guess. In general, I would not advocate discontinuing such a critical part of a combination regimen without substituting something... Read more »

PROTEASE INHIBITOR TREATMENT

I AM HIV POSITIVE, WITH A CD4 COUNT OF 394 AT LAST READING. MY DOCTOR HAD HAD ME ON 400 MG OF RITANOVIR AND 800 MG OF SAQUINAVIR. HE LATER DECREASED MY DOSAGE TO 200 MG OF RITANOVIR AND 400 MG OF SAQUINAVIR. SINCE THIS DECREASE IN DOSAGE, MY VIRAL...

Response from Cal Cohen, M.D., M.S.

Harvard Medical School

The usual doses when combining ritonavir and saquinavir are 400 to 600 mg ofritonavir twice daily plus 400 mg of saquinavir. When you use only 200 mg ofritonavir it may be enough to help increase saquinavir levels, but it'scertainly not enough... Read more »

what is HIV PROTEASE INHIBITORS.

In taking hydroxyzine pam 25 mg,it states if you are on HIV Protease inhibitors, not to use. What is HIV Protease inhibitors?...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

HIV protease inhibitors are a family of HIV drugs (such as Kaletra, Viracept, Lexiva, Reyataz) used chronically for the treatment of HIV/AIDS.... Read more »

are protease inhibitors the cause of lypoatrophy or is hiv

the same as title. is lypoatrophy a side effect of using protease inhibitors or is lypoatrophy a direct cause, oi, of being hiv positive. i am trying to determine whether the treatment providers have some responsibility for the costs of treating...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Fat loss (lipoatrophy) probably is multi-factorial so the answer is both. Aging, longer time with HIV, a lower CD4 count--those factors have been linked to fat loss. Certain HIV drugs (most notably D4T and AZT) have been linked to fat loss. Protease... Read more »

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lipodystrophy from protease inhibitors

Posted by Anonymous, 4 Replies

I have known about my HIV+ status now for 6 years, and God has blessed me with continued good health. I have accessed all the major medications, plus vitamins to help fight the disease. Once I started taking the new protease inhibitors, I started... Read more »

bone density loss due to protease inhibitors

Posted by Anonymous, 1 Reply

Curious as to latest info. on research into bone density loss due to HAART therapy. Most research data i've seen goes back to 99 or 2000. Any new data/research into this? Also any info. on clinical trials currently under way looking into this... Read more »

Protease Inhibitors - Hemophilia bleeds

Posted by akcol

Hi, my fiance is a Long Term NonProgressor - 24 years positive, co-infection HCV, with severe Hemophilia A.

This is a question for the gentlemen with Hemophilia please.
We're requesting any input about any Hemophilic PI increased unusual bleed... Read more »

Abbott pharmaceuticals price gouging protease inh

Posted by BabyPeanut

Editorial, The Center for AIDS (12/15/03)

In a move that startled healthcare professionals and community members alike, Abbott pharmaceuticals announced a price increase of almost 500% for its protease inhibitor ritonavir (Norvir). Norvir is widely... Read more »

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