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When Do Cd4 Cells Start Decreasing

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The Well Project

Understanding CD4 Cells and CD4 Cell Tests

The Basics CD4 Count and HIV CD4 Count and HIV Treatment CD4 Cell Test The Bottom Line The Basics Your immune system protects your body by fighting germs and infections.White blood cells are an important part of your immune system. HIV infects and destroys a type of white blood cell called aCD4 cell (sometimes called a T-cell). As the immune system loses CD4 cells, it becomes weaker and is less able tofight off germs. When it...
Ask the Experts

CD4 Count V. CD4% Count (ABSOLUTE CD4 COUNT VERSUS CD4%, 2010) (WHEN TO START TREATMENT, 2010)

Hi,I was diagnosed with HIV around 15 months ago. Since then my health has been good (especially in the last six months) but my CD4 count has fallen a bit rapidly from 470 to 371 to 324 over this time period. However, my CD4 percentage count has...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,You are correct: The CD4% is generally considered the more accurate indicator of immune integrity, as it doesn't tend to fluctuate as much due to intercurrent illnesses and other non-HIV-related factors. (See below.)Regarding beginning... Read more »

CD4 Count Decrease & VL Decrease, help why is CD4 going down?

Hello Doc,I was diagnosed about a month ago with a CD4 of 187 and a VL of 34,000. After 5 days on Bactrim and Atripla they took me off Bactrim cause I couldn't breathe. Then after a total of 10 days on Atripla only, I had a VL of 130 and a CD4...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Effective HIV meds when they work decrease the HIV level by interrupting production of new virus (the drop in HIV level you experienced is typical of a good response). CD4 (T helper cell ) count recovery is dependent on production of new T cells by... Read more »

cd4 increase but cd4/cd8 ratio decrease

My cd4 increase from 297 to 441 and cd8 increase from 905 to 1617 So the cd4/cd8 ratio is decreasing from 0.33 to 0.27 it looks worse !! even though cd4 is higher.How should I interpret this lab result ?...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
There could be many reasons for this. Did you start treatment? Did your total white blood cell count and total lymphocyte count change between the two time points? Was there an intercurrent illness?MH... Read more »

Undetectable Viral Load with Decreasing CD4 count but improving CD4%

I was diagnosed 2 years ago. At that time, my viral load was 103,000 and my cd4 count was 249. My CD4 % was around 14%. I started on Atripla in July of 2007 and still take it. My Viral load went down to undetectable within a month and has stayed...
Renslow Sherer, M.D.

Response from Renslow Sherer, M.D.

University of Chicago Hospitals
Though your title is 'undetectable viral load with decreasing CD4 cell count', you have actually had an increase in your absolute cell count from the start of treatment from 183 to 267, and an increase in the percentage from 14% to 24%.... Read more »
Connect With Others

IL-2 Induces Sustained CD4 Cell Increases

Posted by Anonymous, 1 Reply
IL-2 Induces Sustained CD4 Cell Increases in HIV-Infected Patients


By Deborah Mitchell

TORONTO, Sep 20 (Reuters Health) - The addition of recombinant interleukin-2 (IL-2) to an HIV antiretroviral therapy produces an increase in CD4+ T-cell counts,... Read more »

my CD4 counts dropped. is this normal?

Posted by Anonymous, 2 Replies
I have been infected for just 8 months and have been on meds. My CD4 counts rose to 416 and i am undetectable in viral load. My question is, last week, my CD4 counts dropped to 386. Is this normal? do they fluctuate? I'm worried that my meds are... Read more »

HELP !! CD4 170 AIDS DIAGNOSIS-- IS THIS THE END?

Posted by Anonymous, 7 Replies
I have been positive and healthy on no meds for the last 8 years. Now my cd4 count which was about 600 is down to 170 and my once undetectable viral load is now detectable. What's the average timeframe a person survives after an AIDS diagnosis ? I... Read more »

CD4 Counts????

Posted by Anonymous, 3 Replies
When I started meds, my cd4 count was 348. Is that in the bad range?
Since I started meds, it went up to 358. Read more »