What Was The Azt

Here's a taste of what TheBody.com has to offer on this topic:

Get the Facts

An Overview of Retrovir (Zidovudine, AZT)

zye-DOE-vyoo-deen Brand Name: Retrovir Other Name(s): AZT, Azidothymidine, ZDV Drug Class: Nucleoside Reverse Transcriptase Inhibitors What is zidovudine? Zidovudine is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). It works by disrupting one of the early steps in the HIV life cycle, called reverse transcription. During normal reverse transcription, HIV's reverse transcriptase enzyme (a type...

Ask the Experts

AZT TONGUE PIGMENTATION- AZT 2 ever?

Hi Doctor Young, Does AZT cause a nasty looking pigmenation (black to purple spots to develop on the inside of the tongue and mouth?) Does the AZT that is offered as medicine today in combination with other drugs still produce this result? AZT...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Zidovudine (ADV, AZT) can cause hyperpigmentation of nails and skin- I suppose that it could cause hyperpigmentation of the tongue, but I am not aware of this personally. Yes, when used in combination, the possibility of side effects remain,... Read more »

AZT (Retrovir) & Pregnancy How to know if your resistient to AZT

In 1988 I had a child. 3 months later I was informed her father tested positive. So did I. The baby did not. 1990 - 1991 I took AZT (Retrovir) 1 pill 5 x a day. Then stopped taking it. In 1993 I became pregnant again. Started taking AZT again...

Response from John L. Sullivan, M.D.

University of Massachusetts, Medical School

The risk of transmitting HIV to your infant is directly linked to your viral load; if your viral load is less than 50 copies/ml your risk is less than 1%; the therapy that reduces your viral load to less than 50 can include many different drugs and... Read more »

azt resistance

what other drugs are being used when a patient develops resistance to azt?...

Response from Renslow Sherer, M.D.

University of Chicago Hospitals

Resistance to AZT takes the form of thymidine associated mutations or TAMs. Full cross resistance appears to occur with D4T (stavudine) when present with AZT. As with most other NRTIs, several mutations are needed before complete resistance to AZT... Read more »

IS AZT AND RESCRIPTOR A GOOD COMBINATION

?...

Response from Thomas N. Kakuda, Pharm.D.

University of Minnesota

AZT (zidovudine) and Rescriptor (delavirdine) is unlikely to suppress HIV unless it is used with a third drug. This combination may be good if the viral load (HIV-RNA) is small and your CD4 count is high. In general, most guidelines (DHHS, IAS,... Read more »

Go to Ask the Experts »

Connect With Others