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What Is The Role Of Integrase In Hiv

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U.S. Centers for Disease Control and Prevention

The Role of STD Detection and Treatment in HIV Prevention

What is the link between STDs and HIV infection? How can STD treatment slow the spread of HIV infection? What are the implications for HIV prevention? Where can I get more information? References Testing and treatment of sexually transmitted diseases (STDs) can be an effective tool in preventing the spread of HIV , the virus that causes AIDS. An understanding of the relationship between STDs and HIV infection can help in the...
Ask the Experts

integrase inhibitors,where are they?

Dr. Frascino, I know we know of three crucial enzymes necessary for HIV to do its dirty work. Protease, reverse transcriptase and integrase. Why havent we created an integrase inhibitor. And where are we as far fusion inhibitors. Or any type of...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Where are they? Well, at present, they are "in the pipeline." Exactly how quickly these and other agents will move through the pipeline into broader-based clinical trials, then on to compassionate use/expanded access programs, then... Read more »

ls isentress integrase inhibitors the future for hiv meds ???

Hi Dr Henry,l have been taking different hiv meds for the past 8 years, and its not much fun with the side effects of the meds, l am reading about isentress integtase inhibitors and would like to know your opinion, is this the new step in hiv...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Raltegravir is a promising new HIV treatment known as an integrase inhibitor. It has mostly been used in patients with resistant virus in complex regimens where it has performed well. It has to be taken twice a day. So far it appears well tolerated... Read more »

Integrase Inhibitor

Dr. Young, I am very interested to hear your thoughts on Integrase Inhibitors. -Do you think they will be successful in developing one? -Do you think it can be potentially used as a monotherapy?-Generally what are your thoughts?...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your questions.Inhibitors of HIV integrase have been under investigation for some time, though none are currently in advanced clinical trials. There have been a couple of aborted candidate compounds, one from Merck, another from... Read more »

How is s-1360 Integrase Illustrating in Test Results?

Dr. Young,S-1360 Integrase, Yes or No, or possibly?Newman...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Developement of S-1360, an experimental HIV integrase inhibitor has been terminated, because the medication is very poorly absorbed in the human gastrointestinal tract. BYps-- please, only post your question once, not ten times.... Read more »
Connect With Others

Integrase Inhibitor

Posted by Survivor
I just wanted people realize there is hope and continued very active DRUG DISCOVERY!

Merck, Gilead Release Strong Findings From Clinical Trials of Experimental Integrase Inhibitor Antiretroviral Drugs

Whitehouse Station, N.J.-based Merck and Foster... Read more »

Caretaker and Lover Conflicting Roles?

Posted by Ronnie, 1 Reply
Hi everyone!

So, my partner and I are both positive. He has AIDS, I'm recently seroconverted (5-04).

He suffered from some OI's in December, but he's doing well now. But, somehow I have taken on the role of caretaker. I take it upon myself to worry... Read more »

Seeking Serodiscordant Role Models

Posted by AboutTimex, 3 Replies
Two guys here, mixed status, looking for a little advice. We've been together a few months and are navigating how to deal with our neg/pos match up. We'd like to hear from some similar couples about their experiences within a serodiscordant... Read more »

Today's LA Times Article - Integrase Inhibitors

Posted by Anonymous
Very hopeful! (Despite the sad title.)

http://www.latimes.com/news/nationworld/nation/la-me-salvage2jan02,0,1565232,full.story?coll=la-home-headlines Read more »