What Is A Drug Called Zidovudine

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Zidovudine (Retrovir, AZT)

What Is Zidovudine? Zidovudine (Retrovir) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. It is manufactured by ViiV Healthcare. The patent on zidovudine expired in 2005 and several generic versions have been approved. Several are available under PEPFAR (see Fact Sheet 475 ). Zidovudine is also known as azidodeoxythymidine, AZT or ZDV. Zidovudine was the first drug approved for the treatment of...

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atripla and zidovudine

if somebody becomes resistant to atripla components would he necessarily become resistant to zidovudine as well? i hope not because in a paper i saw point mutations caused by 3 components of atripla are absolutely different from that caused by...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Hello and thanks for posting.There is a potential for cross resistance among the components of treatment. This means that prolonged treatment failure of one NRTI regimen has the potential to cause significant cross resistant to other medications of... Read more »

Zidovudine alone given to baby

Good day doc. I am HIV positive, on Nevirapine and lamzid, last test CD4 count 836, viral load undetectable. Just had a baby on 30 Nov 2011 via C-Section. My baby is being given 5ml Zidovudine 6 hourly. My understanding is that Zidovudine should be...

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine

Assuming you were taking those HIV meds during your pregnancy, then yes, zidovudine as a single HIV drug for 6 weeks after birth is appropriate to give as prophylaxis to your baby.... Read more »

zidovudine, didanosine, kaletra

Is the above combination suitable for one considered to be resistant to combivir and effavirenz? I have come across these in the internet. My doctor thinks I could be resistant to combivir and effavirenz. I have been on them for 2 years. Due to...

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation

Hello,Ideally speaking, if resistance develops to a HAART (highly active antiretroviral therapy) regimen, I recommend getting a resistance test to help guide the choice of the next regimen. If resistance testing is not an option in Zimbabwe and your... Read more »

Underdosage of Zidovudine

Dear SirI am writing for the 2nd time. My son aged 5 years has been recently diagnosed as HIV+ His CD4 is 384. His doctor started him on Zidovudine 6ml twice a day, Lamivir 6.5 ml twice a day, and Nevirapine (initially 6 ml once a day). His weight...

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES

Thanks for your post.This reply comes from our good friend and colleague, Andy Pavia, MD from University of Utah:I don't think there is any risk at all from 2 weeks of underdosing of zidovudine. First of all, zidovudine resistance develops... Read more »

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