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What Is Isentress

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Isentress

Brand name: Isentress Generic name: raltegravir, or RAL Class: Integrase inhibitor (integrase strand transfer inhibitor, or INSTI) Manufacturer: Merck and Co., www.isentress.com , (800) 622-4477 AWP: $1,171.31/month Standard Dose: One 400 mg film-coated tablet twice a day, with or without food, with no dietary restrictions. Can be taken by children two years or older. Dosing is based on weight for children 2-11 years old. A new...
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Isentress and Headache

I've been on Isentress (and Truvada) since early December 2007. My numbers are good but I have a constant dull headache. It's sort of a feeling like my brain is contracted. I've taken NSAID's but they don't affect it at all....
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
I have heard some anecdotal reports of headaches of spikes in blood pressure from raltegaravir (Isentress). The only way to find out for sure is to switch off the Isentress on a trial basis (ie use a NNRTI or boosted PI) depending on your past... Read more »

Isentress: how close to every 12 hours?

Hello and thank you for your time. I appreciate it. I'm on Isentress and Truvada and am doing fine. I take the Isentress almost exactly at 12 hour intervals (isentress at 7am and isentress + truvada at 7 pm. It would be more convenient to...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hi and thanks for your post.I believe that your time interval is fine, especially when backed by the knowledge that your viral loads are "doing fine".Be well,BY... Read more »

Am I developing resistance to Truvada/Isentress?

I was on Viracept, Epivir, Zerit for 15 years. I never developed resistance. Then one year ago, switched to Truvada, Isentress. Next, me and my doctor decided to switch to Epzicom, Isentress, but took a viral load test (plus a hla b5701 test) before...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thanks for posting.A single viral load of 129 doesn't not necessarily mean drug resistance or treatment failure. Indeed, most viral loads in this range (following an undetectable test, and with good adherence) are usually blips,... Read more »

double dose os isentress?

I started Truvada/Isentress PEP last week and my adherance so far has been excellent, and the side effects pretty minimal. I usually take truvada/isentress at 9am each morning and isentress at 9pm in the evening.because of my schedule, I usually...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Should be no problem. Double doses of raltegravir (Isentress)once daily (entire dose at once) have been studied and though generally well tolerated the effectiveness of the once daily dosing was below the effectiveness of twice daily dosing so... Read more »
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isentress and truvada

Posted by anfan4, 2 Replies
im been on isentress and truvada for month and half and notice increased in blood pressure and any else had this problem. Will isentress cause this problem. Read more »

Isentress Drug - Side Effects?? HELP

Posted by design36, 1 Reply
I have been taking Isentress for about a month...Adnormal dreams, Insomnia, Excessive fatique have been side effects and seem to be ones for a lot of people. Does anyone have experience with this drug? Did the side effects get better? How long... Read more »

Isentress & Side Effects

Posted by design36, 3 Replies
I have been taking Isentress for about a month...Adnormal dreams, Insomnia, Excessive fatique have been side effects and seem to be ones for a lot of people. Does anyone have experience with this drug? Did the side effects get better? How long... Read more »

anyone taking Isentress and Invirase combination?

Posted by nevereasy
Isentress is a relatively new therapy. My Dr just added it to my mono therapy of Invirase (boosted with Norvir). I have been undetectable for two years on the Invirase but my Tcells never get over 300. He added Isentress. I have had bad reflux ( not... Read more »