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What Is Epzicom Used For

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AIDS InfoNet

Epzicom/Kivexa (Abacavir + Lamivudine)

What Is Epzicom? Epzicom is a pill that contains two drugs used to fight HIV: abacavir (Ziagen) and Epivir (lamivudine, 3TC). Epzicom is manufactured by ViiV Healthcare. Outside the US, it is called Kivexa. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). The drugs in Epzicom are called nucleoside analog reverse transcriptase inhibitors, or nukes. These drugs block the reverse transcriptase enzyme. This enzyme...
Ask the Experts

Kaletra / Epzicom - Would like holiday from Epzicom

My CD4 hovers around 400. Viral load undetectable for three years. Take Kaletra and Epzicom, no other medications. Experiencing some fatigue for a couple of years now. I know one common side effect of Epzicom can be fatigue. Would like to take a...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
Fatigue is not that common with Epzicom compared to other drugs and is common in general population so hard to pin down if Epzicom is primary cause. Switch to alterantive drug (ie Truvada or raltegravir) with observation for several months to track... Read more »

I Just Combined Expired Reyetaz with New Rey . . . Combo with Epzicom

I am taking Epzicom with this . . . not Norvir, so would it matter? I understand extreme condtions might decay meds, but with Epzicom is other problem possible?I Just Combined Expired Reyetaz with New Rey . . .Feb 3, 2011The expired bottle was over...
Joseph McGowan, M.D., F.A.C.P.

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital
Miriam,The difference is not so much with the epzicom, it is that the norvir would "boost" up the levels of the reyataz, so it's potency may be enhanced. Without the norvir there is less "wiggle room" if the drugs are past... Read more »

Epzicom Reaction

I recently tried moving from Truvada to Epzicom. I could only stay on Epzicom for two weeks as I felt like I was taking speed. Lost 4 Lbs and could not sleep either without ambien. Have you had any patients experience this? It's not noted as...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Thanks for your post.Based on your switch to Epzicom and switch back to Truvada, it would indeed seem like your symptoms are related to one of the medications in Epzicom. I can't say that I have heard of this reaction, despite many years of... Read more »

Isentress & Epzicom

It seems that most of the studies have paired Isentress with Truvada. Is there any reason to believe that Epzicom would not work equally as well with Isentress? Thanks....
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
Hello and thank you for your post.Provided that the patient is genetically screened for abacavir hypersensitivity (allergy), there's no particular reason why Epzicom (abacavir/3TC) shouldn't work with the integrase inhibitor, Isentress... Read more »
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New to Epzicom...Help with side-effects

Posted by Keoki, 1 Reply
Anybody out there on Intellence and Epzicom? I'm new to Epzicom. I had to stop Truvada, because of kidney function issues. I'm having a bit of a hard time adjusting to the Epzicom...nausea, lethargy, and just not "feeling right." Any information... Read more »

Reyataz/Norvir/Truvada/Epzicom...morning or night?

Posted by Anonymous, 3 Replies
I'm starting in a study, and I just got my meds today. I'll be on Reyataz boosted with Norvir, and either Epzicom or Truvada (I won't know which).

Does anyone know if there are any advantages to taking these meds in the morning as opposed to the... Read more »

Epzicom + Reyataz?

Posted by Anonymous, 1 Reply
Hi.
I have just been diagnosed with a CD4 count of 11, and a viral load of 820,000.
I may start teatment with Epzicom + Reyataz and I wanted to know if anybody else had started with this regimen, or is currently on it, and what they thought of it?
Thank... Read more »

Reyataz,Norvir, Kivexa [abacavir/3TC, Epzicom].

Posted by Mondo
Is there anyone here at the forum taking the following cocktail?
I'm taking Reyataz[atazanavir], Norvir [ritonavir] and Kivexa [abacavir/3TC, Epzicom]. I would be interested to know how you are going with it and any problems or side effects that you... Read more »