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What Is Didanosine Used For

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Get the Facts
AIDS InfoNet

Didanosine (Videx, ddI)

...Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively approved under PEPFAR (see Fact Sheet 475 ). Didanosine is a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse...
Ask the Experts

Vision Changes with Didanosine

My partner had his meds changed two months ago and two weeks ago had a sudden change in vision. He now has to squint to focus day or night and is seemingly more light sensitive than normal. We discussed this with our doctor who said we most likely...
Graeme Moyle, M.D.

Response from Graeme Moyle, M.D.

Chelsea and Westminster Hospital
...prescription lenses can occur quickly at some ages (esp mid-40s). This is a change in lens shape. Reports mostly with high doses of ddI of visual changes were related to retinal (back of the eye) problems and were generally reversible on drug... Read more »

neuropathy pain (didanosine+stavudine+efavirenz)

Dear Dr Robert J. Frascino, I'm sure many patients email you a lot of times regarding this matter. But I really really hope you won't get bored. I'd really really appreciate your help, time and patience!My question is:My father CD4 recently = 480He...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
...Hi Tom,Didanosine (ddI) plus stavudine (d4T) is no longer a recommended combination! It has been found to be less effective and substantially more toxic Read more »

zidovudine, didanosine, kaletra

Is the above combination suitable for one considered to be resistant to combivir and effavirenz? I have come across these in the internet. My doctor thinks I could be resistant to combivir and effavirenz. I have been on them for 2 years. Due to...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Ideally speaking, if resistance develops to a HAART (highly active antiretroviral therapy) regimen, I recommend getting a resistance test to help guide the choice of the next regimen. If resistance testing is not an option in Zimbabwe and your... Read more »

DIDANOSINE

Could ddI chewable tablets be taken once a day?
Judith A. Aberg, M.D.

Response from Judith A. Aberg, M.D.

Washington University, St. Louis School of Medicine
Yes, but only the 200 mg tablet can be used because of the amount of buffer in the tablet. Videx does come in a new capsule formulation which is made for once daily dosing. Unless you have difficulty swallowing capsules, you may want to consider... Read more »
Articles
AIDSinfo

An Overview of Videx (Didanosine, ddI)

... Brand Name: Videx EC, Videx Other Name(s): BMY 40900, BRN 3619529, CCRIS 805, Didanosina, Dideoxyinosine, HSDB 6548, ddI Drug Class: Nucleoside Reverse Transcriptase Inhibitors Didanosine, also known as ddI or Videx, is a type of... Read more »
U.S. Food and Drug Administration

Important Changes to Videx (Didanosine) Labeling

...sections in both package inserts are outlined below. Other minor changes to the package inserts were made for consistency. In addition the Videx pediatric powder package insert was converted to Physician Labeling Rule (PLR) format. Summary of... Read more »
U.S. Food and Drug Administration

Videx EC/Videx (Didanosine) Label Change Reflects Potential for Serious Liver Disorder

...The decision to use this drug, however, must be made on an individual basis between the treating physician and the patient. Additional Information for Patients Didanosine is a prescription medication used along with other drugs to treat... Read more »
U.S. Food and Drug Administration

Early Communication About an Ongoing Safety Review of Ziagen (Abacavir) and Videx (Didanosine)

...nucleoside reverse transcriptase inhibitors (NRTIs). The NRTIs included in the analyses were zidovudine, stavudine, abacavir, didanosine, and lamivudine. No analyses were conducted evaluating the risk of heart attack when patients take tenofovir... Read more »
Connect With Others

Early HIV Treatment Failure Linked to Didanosine/T

Posted by TwinsDad, 1 Reply
...NEW YORK (Reuters Health) Aug 23 - The combination of the antiretroviral agents didanosine, tenofovir, and efavirenz is associated with a high virological failure rate in treatment-naive patients with HIV, British investigators Read more »

Bristol Myers Squibbs: Videx

Posted by Anonymous, 2 Replies
Gentlemen, Stay away from Videx it infected my pancreas and made me diabetic, apprantly it does that to a high percentage of people on it or as I also understand kills another hign percentage of them. What does Bristol Myers Squibbs do? Sell death... Read more »

Urge segunda opinion

Posted by Edy, 1 Reply
...El problema es que me hicieron un genotipo y segun el resultado sali resistente a: Efavirenz Nevirapine Lamivudine Didanosine Abacavir Emtricitabine Mi doctora me pinto un panarama muy pesimista y medijo que solo tengo una opcion de esquema:... Read more »

50% of HIV+ Develop Neurocognitive Impairment

Posted by ScotCharles, 3 Replies
...remembering, planning, making decisions, attentional abilities, concentration; those kinds of skills are under "neurocognitive." In addition, a subset of these patients received brain-imaging studies, including studies of the structure of their... Read more »