What Is Darunavir

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An Overview of Prezista (Darunavir, TMC114)

dar-UE-na-vir Brand Name: Prezista Other Name(s): DRV, darunavir ethanolate Drug Class: Protease Inhibitors Approved Use: Treatment of HIV Infection WARNING: Darunavir can cause serious, life-threatening side effects. These include liver problems and severe skin reactions or rash. Contact your health care provider right away if you have any of the following symptoms that may signal liver problems: ...

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Darunavir or not to Darunavir + Low WBC

Hi Joe,I have another question for you. I have recently seen my consultant, and he has suggested changing PI's from Atazanavir to Darunavir. He quotes a few studies that suggest additional benefit for DRV. At the moment I'm undetectable on...

Response from Joseph McGowan, M.D., F.A.C.P.

North Shore University Hospital

Michael,Thanks for your questions. Darunavir is now approved for both first line treatment as well as for treatment experienced patients. It is a very potent protease inhibitor, but potency does not seem to be an issue with your regimen since you... Read more »

Darunavir, Ritonavir and Augmentin

I have been prescribed Augmentin for the treatment of bronchitis. Can this be taken with Darunavir and Ritonavir?...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Generally OK to take darunavir/ritonavir with Augmentin. KH... Read more »

darunavir & CNS effects

My BF is on darunavir (among others) - since he has started this drug, he has been experiencing patches of dizziness (he calls it "wonkiness) after taking it. Would this be from the darunavir, or is it more likely to be caused by interactions...

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine

Either the daurunavir or the accompanying ritonavir may be the most likely of his HIV drugs to cause some periods of dizziness. For most patients that complaint stabilizes/settles down after several months. KH... Read more »

Re darunavir.

GDay Doctor. I have an ongoing issue with (some) yellowing of the eyes and was told it was most likely due to atazanavir. My billirubum (?) is nearly 50. I also take tenofovir,ritonovir,3tc,acyclovir. 28yrs poz. undetectable 8yrs. 950 tcells....

Response from David Wohl, M.D.

University of North Carolina - Chapel Hill

Atazanavir (Reyataz) is well known to cause a harmless increase in bilirubin in the blood that can cause yellowing of the whites of the eyes.Darunavir is an excellent alternative. It also is taken with Norvir. The effect of darunavir on... Read more »

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anal problems....

Posted by erik1964

I have been on hiv medication for more than 10 years now, I noticed that Viramune gives me no anal pleasure any more (but also did Darunavir). Because of the side effects I don't have lots of choices for therapy. Now I am on Truvada (really good... Read more »

What should I think?

Posted by motherinlaw, 9 Replies

I will try not to make this too long...my son called yesterday and told me his wife was not doing well. My HIV negative son and three HIV negative grandchildren may soon lose their HIV positive wife and mother.
My son and daughter-in-law seem not to... Read more »

Thanks for your support and any more advice?

Posted by motherinlaw, 3 Replies

I want to thank everyone for their support and help. I posted this in response to my own previous posting and felt it might have gotten lost in the shuffle and so am reposting.

I have just spoken to my son again. He was finally able to convince his... Read more »

New Drug - TMC114

Posted by Survivor, 1 Reply

Don't Let TMC114 Cost More Than Kaletra, Advocates Urge

We may be only days away from an announcement that the U.S. has approved a
new HIV medication: TMC114 (darunavir), a protease inhibitor that may be
especially helpful for people with... Read more »

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