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What If I Miss A Dose Of DdI

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Get the Facts
AIDS InfoNet

Didanosine (Videx, ddI)

... What Is Didanosine? Who Should Take Didanosine? What About Drug Resistance? How Is Didanosine Taken? What Are the Side Effects? How Does Didanosine React With Other Drugs? What Is Didanosine? ddI (Videx) is a drug used as part of antiretroviral therapy (ART). It is manufactured by Bristol-Myers Squibb and by Barr Laboratories. Didanosine is also known as ddI or dideoxyinosine. Generic versions have been tentatively approved
Ask the Experts

can ddi, abc and aluvia taken together

when we had kaletra we recommended DDI early morning on empty stomach and one hour later ABC and kaletra. Now we have aluvia which can be taken without regard to food. Can all be taken as one dose on empty stomach?
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Kaletra,lopinavir/ritonavir, tablet formulation) and abacavir (Ziagen, ABC) can indeed be taken without regard to food- so a regimen of Aluvia, ddI and abacavir can all be taken together as a once-daily regimen.BY Read more »

DDI - Peripheral neuropathy

I have been HIV positive since 1985. I have severe neuropathy. I havedeveloped resistance to the antivirals I've been taking.My doctor has ordered Didanosine (DDI). What are the chances of the DDImaking my neuropathy worse? THANKS FORYOUR HELP!
Cal Cohen, M.D., M.S.

Response from Cal Cohen, M.D., M.S.

Harvard Medical School
...Yes, if you have severe neuropathy, ddI could definitely make yourneuropathy worse. The "d-drugs" (ddI, ddC, or d4T) are contraindicatedin someone who has severe neuropathy. Read more »

Tenofovir & Didanosine Dosing

Could you clarify what you think are reasonable dosages for tenofovir and didanosine when taken in combination? My friend was on 400mg daily didanosine EC (2hr after meal)and 300mg daily tenofovir with meal and was recently switched to combined...
Brian Boyle, M.D., J.D.

Response from Brian Boyle, M.D., J.D.

Cornell University, Weill Medical College
...The data on how to adjust Videx (didanosine) when given with Viread (tenofovir) is not yet available, but there are studies currently underway to provide further guidance. Read more »

viread/ddi

According to drug company literature and different source of imformation viread is supposedly less toxic and not as likely to cause mitochondrial toxcity as ddi.How can this be,if they are both anologues of adenine?I would think the side effects...
Benjamin Young, M.D., Ph.D.

Response from Benjamin Young, M.D., Ph.D.

Rocky Mountain CARES
...Thanks for your question.Yest both didanosine (Videx) and tenofovir (Viread) are both adenosine analogues. Past this, the two drugs have very dissimilar structures, and dissimilar Read more »
Articles
AIDSinfo

An Overview of Videx (Didanosine, ddI)

... Brand Name: Videx EC, Videx Other Name(s): BMY 40900, BRN 3619529, CCRIS 805, Didanosina, Dideoxyinosine, HSDB 6548, ddI Drug Class: Nucleoside Reverse Transcriptase Inhibitors Didanosine, also known as ddI or Videx, is a type of... Read more »
The Body PRO

Abstract No. 402:Phase I/II Dosing Study of Once-Daily Hydroxyurea (HU) Alone vs Didanosine (ddI) Alone vs ddI + HU

...In earlier studies, hydroxyurea, when added to DDI or D4T increased the activity of a single or dual nucleoside therapy by 0.5 to 0.7 log 10 copies/mL. The authors, in this placebo Read more »
The Body PRO

Abstract No. 402: Phase I/II Dosing Study of Once-Daily Hydroxyurea (HU) Alone vs Didanosine (ddI) Alone vs ddI + HU

...a phase I/II, randomized, placebo-controlled five-arm study comparing HU alone at two doses (1000 mg a day and 1500 a day), ddI alone (200 mg twice a day), and ddI/HU in treatment naïve and experienced subjects. The HU groups had ddI added after... Read more »
The Body PRO

Safety and Efficacy of Once-Daily Dose of Didanosine (DDI)

...Dr. E. Martinez and colleagues from Barcelona, Spain, reported on 80patients who received ddI once a day, plus D4T 40 mg bid, with or withoutsaquinavir or indinavir. The mean baseline CD4 count was 178 cells/mm3, andthe Read more »
Connect With Others

taking ddi

Posted by Anonymous, 1 Reply
...Taking ddi (Videx)? Do you drink alcohol? My Dr. says I should have no alcohol as it increases the risk of getting pancreatitis. Read more »

Sustiva or DDI/hydroxurea

Posted by Anonymous, 2 Replies
...I am a female recovering addict and have been clean for over ten years. I am getting real weird side effects from Sustiva and even though I started taking Read more »

My partner was put on DDI

Posted by Anonymous, 1 Reply
...Hi, My partner is HIV+ and has recently been put onto DDI and AZT. I think, as a consequence, has become one of the most unfriendly, annoying people in the world. Is this common, have Read more »

Two weeks down and a life time to live

Posted by trulife, 2 Replies
Well folks...it's the end of two weeks on Atripla and so far things are going well. Side effects have been limited and are now subsiding. My biggest problem so far is swallowing the pill. I have always had trouble swallowing pills...go figure...a... Read more »