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What Happens When The New Hiv Cell Leaves The Infected Host Cell

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San Francisco AIDS Foundation

How HIV Damages the Immune System

Introduction The basic structure of HIV is similar to that of other viruses (Figure 1 ). HIV has a core of genetic material surrounded by a protective sheath, called a capsid . The genetic material in the core is RNA (ribonucleic acid), which contains the information that the virus needs in order to replicate (make more copies of itself) and perform other functions. You can think of RNA as the set of rules the virus follows in order to...
Ask the Experts

hiv outside the host

Dr. Bob,We have all read that hiv does not survive well outside the body, but what exactly happens to it when it leaves the host? Does the cell wall collapse, or do the glycoproteins get degraded, or does the capsid "burst", or etc..?...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hi,HIV is an extremely tiny piece of genetic material that gets integrated into the genetic material of host cells (CD4 cells, for example). HIV does not survive without viable host cells. Hence, when HIV and/or HIV-infected cells are outside of the... Read more »

White Blood Cells during primary HIV infection

I am confused about this whole white blood cell thing. There are doctors who believe that during acute retroviral syndrome/primary HIV infections that white blood cell and lymphs are low, and others say that they would be high, which is true??...
Bruce Dezube, M.D.

Response from Bruce Dezube, M.D.

Harvard Medical School
I don't believe there is enough published to say definitively what happens to white cells during the acute retroviral syndroma/primary HIV infection. In general, in viral infections, the white blood cell count typically does go down; this is... Read more »

The effect of protease inhibitor in cell-to-cell transmission

Dear professor,In virus to cell transmission, protease inhibitors cause infected cells to produce immature virus particles that are non-infectious. Hence, these drugs decrease the number of new infectious virions that are produced. How do protease...
Keith Henry, M.D.

Response from Keith Henry, M.D.

University of Minnesota, School of Medicine
By decreasing significantly number of new infectious HIV particles propagation of HIV infection with then body (infection of new target cells such as CD4 T-helper cells) is greatly diminished. Cell to cell transmission of HIV overall less of a... Read more »

gene therapy via blood stem cells new treatment for hiv ???

Hi Dr Bob,l am recently infected with hiv and guess what you have become my hero, please keep up the great work you do for us hivers around the world,l read all your posts and you are the man period...l need to start treatment asap cd4 300 and...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello Pat,Thanks for your kind comments.The results of the OZ1 stem cell gene therapy phase II clinical trial were exciting and encouraging in equal measure. Dr. Ron Mitsuyasu at UCLA is an excellent HIV/AIDS/oncologist physician specialist who has... Read more »
Connect With Others

HIV leave host in very short time

Posted by tobeabetterman, 2 Replies
Hi experts , I post this one because I read something from another famous forum and find many people confused on it ( including me , once have a same anxiety ).
That's also for many of my friends known form internet , and they all confused about... Read more »

T Cells

Posted by Anonymous, 3 Replies
I have consistantly tested negative on several tests over the past two years. However, I keep getting symptoms of hiv and my t cells are lurking around the 400 range. I have more test results comminmg back on feb 4th.

Is there anyone else out there... Read more »

T-cells dropping and Interferon

Posted by Anonymous, 2 Replies
HI, my son's father is HIV+ and has HEPc also.. his viral count is undecectable and t-cell count has always been around 400+..he started interferon for the hepc about 4 weeks ago. 2 weeks ago he had blood drawn and his T cell count was under 300..... Read more »