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What Happens When Cd4 Decreases

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AIDS InfoNet

CD4 (T-Cell) Tests

What Are CD4 Cells? CD4 cells are a type of lymphocyte (white blood cell). They are an important part of the immune system. CD4 cells are sometimes called T-cells. There are two main types of CD4 cells. T-4 cells , also called CD4+, are "helper" cells. They lead the attack against infections. T-8 cells (CD8+) are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected...
Ask the Experts

CD4 Count V. CD4% Count (ABSOLUTE CD4 COUNT VERSUS CD4%, 2010) (WHEN TO START TREATMENT, 2010)

Hi,I was diagnosed with HIV around 15 months ago. Since then my health has been good (especially in the last six months) but my CD4 count has fallen a bit rapidly from 470 to 371 to 324 over this time period. However, my CD4 percentage count has...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,You are correct: The CD4% is generally considered the more accurate indicator of immune integrity, as it doesn't tend to fluctuate as much due to intercurrent illnesses and other non-HIV-related factors. (See below.)Regarding beginning... Read more »

Undetectable Viral Load but CD4 is still decreasing, can you help? (DISCORDANT RESPONSE TO ANTIRETROVIRAL THERAPY, 2011) (CD4 COUNTS NOT INCREASING DESPITE UNDETECTABLE VIRAL LOAD, 2011)

Hi Dr Bob, can you help? My partner has been taking Atripla since december and for the last couple of months has had a undectable viral load, two months a go his CD4 count was 120, then since then it has been dropping and yesterday was told it was...
Robert J. Frascino, M.D.

Response from Robert J. Frascino, M.D.

The Robert James Frascino AIDS Foundation
Hello,Your partner is experiencing a discordant response to his antiretroviral regimen (Atripla). His virologic response is excellent, as his HIV plasma viral load is undetectable. However, his immunological response remains poor, as his CD4 count... Read more »

CD4 count decrease and viral load decrease

Iam currently on second line Hiv treatment and taking a combination Truvada and Aluvia.After noticing that my cd4 count had dropped to 172 from 242 but my viral load has decreased from from about 8000 to about 1500 i took a sensitivity test which...
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
There are likely several options to replace emtricitabine with another one or two HIV meds that your virus is not resistant to. I don't think it's wise to continue with your current regimen and maintaining a detectable viral load will lead... Read more »

Viral load and CD 4 count decreasing while on ARVs

I have been on ARVs for over a year, viral load is decreasing but CD4 count is also decreasing it is 17 from 37. I look and feel healthy what is happening and what am I supposed to do....
Mark Holodniy, M.D., F.A.C.P., C.I.C.

Response from Mark Holodniy, M.D., F.A.C.P., C.I.C.

Stanford University, School of Medicine
You don't indicate what your regimen is, what your viral load was when you started and what it is now, and it's not clear if those numbers are your absolute CD4 count or CD4%. If your viral load is still not undetectable, and your are... Read more »
Connect With Others

Worried CD4 count and viral load

Posted by New33, 4 Replies
Hi everyone,

I've never used this service so please bare with me explaining my question.

I go to the MSHC in Melbourne / Australia but felt a little rushed of late to ask some question about my results for HIV and hoping this post finds its way to... Read more »

Increase your CD4 count

Posted by prana, 2 Replies
Breathing will help increase your CD4 count. The body needs extra oxygen in the blood to fight disease. To help the body do the breathing exercises.Keep a note of your CD4 count each time you do a test. Also the body will generally feel better. You... Read more »

CD4 count at 8--gained weight

Posted by Anonymous, 2 Replies
Oh my I just got cd4 count at 8--down from a whopping 35 last year--freaked out my ID Doc who didn't even look at cd8 or resistance or any of that because if you're at 8 it isn't too great!

He decided to Difllucan me again on a permanent basis. He... Read more »

Lower CD4s

Posted by Anonymous, 1 Reply
My viral load has been undetectable for a couple of years but my CD4s have been on a steady decline (now at 199). My doc is not sure what is happening and the Experts on The Body don't seem to have answers either. I would love to discuss this issue... Read more »